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Database Content<br />

Page 6 | GENESEQ on STN (DGENE) Workshop Manual<br />

Database content<br />

GENESEQ (file DGENE) is an intellectually annotated database of protein and nucleic<br />

sequences indexed from the basic patent publications of the 47 patent authorities of the Derwent<br />

World Patents Index ® (DWPI SM ) (file WPINDEX) 1 . DGENE is updated once every two weeks.<br />

Sequences in DGENE<br />

� Protein and nucleic acid sequences from 1981 to date<br />

� From the basic patent publications of 44 patent authorities<br />

� Individual records for sequences that differ by even one nucleotide or amino acid<br />

� Sequences with natural, common, uncommon or non-natural nucleotides or amino acids<br />

� Polypeptide and protein sequences of >3 amino acid residues<br />

� Nucleic acid sequences of >9 nucleotides<br />

� Nucleic acid primer and probe sequences of any length<br />

� Sequence identifying information in description and keyword fields<br />

� Features table for annotations and modifications<br />

DGENE records also contain<br />

� English abstracts per sequence written by Thomson Reuters experts<br />

� Enhanced patent titles from DWPI<br />

� Bibliographic Patent information from DWPI<br />

� Cross-reference Accession Numbers from corresponding DWPI records<br />

DGENE offers three sequence searching methods<br />

� BLAST ® for advanced similarity searching using the NCBI BLAST algorithm<br />

� GETSIM for advanced similarity searching based on the FastA algorithm<br />

� GETSEQ for simple sequence queries<br />

DGENE also provides<br />

� Offline batch sequence searching<br />

� Current awareness Alert feature for similarity searching<br />

1 See: http://thomsonreuters.com/products_services/science/science_products/a-z/geneseq/

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