note - FIZ Karlsruhe

Introduction to similarity searching
Sort the answers by descending similarity score
Answer set arranged by accession number; to sort by descending
similarity score, enter at an arrow prompt (=>) "sor score d".
=> SOR SCORE D
PROCESSING COMPLETED FOR L2
L3 45 SOR L2 SCORE D
Sort the sequences by patent family with FSORT
=> FSORT L3
SET SMARTSELECT ON
SET COMMAND COMPLETED
SET HIGHLIGHTING OFF
SET COMMAND COMPLETED
SET AUDIT OFF
SET COMMAND COMPLETED
SEL L3 1- PN,APPS
L4 SEL L3 1- PN APPS : 63 TERMS
'L4' DELETED
L4 45 FSO L3
SET SMARTSELECT OFF
SET COMMAND COMPLETED
SET HIGHLIGHTING ON
SET COMMAND COMPLETED
SET AUDIT ON
SET COMMAND COMPLETED
10 Multi-record Families Answers 1-37
Family 1 Answers 1-3
Family 2 Answers 4-6
Family 3 Answers 7-16
Family 4 Answers 17-18
Family 5 Answers 19-22
Family 6 Answers 23-24
Family 7 Answers 25-31
Family 8 Answers 32-33
Family 9 Answers 34-35
Family 10 Answers 36-37
8 Individual Records Answers 38-45
0 Non-patent Records
Display answers with DISPLAY PFAM
=> DISPLAY PFAM
ENTER (L4) OR L#: L4
ENTER PATENT FAMILY NUMBER OR RANGE (1): 1-
ENTER ANSWER NUMBER OR RANGE (1): 1
ENTER DISPLAY FORMAT (BIB): TRI OS SCORE ALIGN
Page 42 | GENESEQ on STN (DGENE) Workshop Manual
FSORT can be used to group together
sequence hits from the same publication,
application and/or patent family for a more
efficient review of the results retrieved.
FSORT (L4) of the 45 BLAST answers (L3)
reveals 18 patent family groups: 10 with
multiple sequence answers for the search,
and 8 with just one sequence hit each.
Similarity Sort Order for L4:
� The first record from Family 1 (Answer 1) is the best
answer from the multi-record subset
� The first record from Family 2 (Answer 4) is the most
similar sequence from the next best multi-record family
� The first record of the 8 Individual Records (Answer 38) is
the most similar from the individual-record subset.
DISPLAY PFAM is used
here to display just the first
sequence hit from each
multi-record patent family