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note - FIZ Karlsruhe

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Protein SUBSEQUENCE Search<br />

Sequence Code Match Searching<br />

SUBSEQUENCE searching is a method for searching amino acid sequence fragments within<br />

larger polypeptides. The following example illustrates the use of this search technique.<br />

Search Question: Find patents for proteins that match the following string<br />

DSDGLAPPQHLIRV – look for exact matches, family equivalents, or<br />

embedded in larger sequences of 200-400 amino acids<br />

Search Strategy<br />

To find protein subsequence answers DGENE…<br />

Step 1 Run the sequence search<br />

Step 2 Limit to the sequence length range<br />

Step 3 Display the sequence and patent information<br />

Run the subsequence search<br />

=> RUN GETSEQ DSDGLAPPQHLIRV/SQSP<br />

RUN GETSEQ AT 19:15:37 ON 30 DEC 2010<br />

COPYRIGHT (C) 2010 <strong>FIZ</strong> KARLSRUHE GMBH<br />

L1 RUN STATEMENT CREATED<br />

L1 400 DSDGLAPPQHLIRV/SQSP<br />

Limit by sequence length range<br />

=> S L1 AND 200-400/SQL<br />

3823320 200-400/SQL<br />

L2 318 L1 AND 200-400/SQL<br />

GENESEQ on STN (DGENE) Workshop Manual | Page 109

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