Catalytic Synthesis and Characterization of Biodegradable ...

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Chapter 6 used to characterize the resultant block copolymer, the disappearance of the resonance absorption from the protons in the PTAm segment indicated that the N-H groups had been oxidized into paramagnetic nitroxyl radicals that would induce no magnetic resonance absorption. The GPC results (Figure 6.4) also revealed the two obtained block copolymers with unimodel GPC traces, demonstrating the successful preparation of the block copolymers. Figure 6.3 1 H NMR spectra of (A) MPEG-b-PTAm precursor polymer; (B) MPEG-b-PLA-b-PTAm precursor polymer. Figure 6.4 GPC traces of MPEG-b-PTAm and MPEG-b-PLA-b-PTAm ‐ 118 ‐
6.4 Micelles preparation and characterization Synthesis of Amphiphilic Triblock Copolymers of Acrylamide, Lactate, and Ethyleneoxide The micelles were prepared by dialysis method. The weighted block copolymer was dissolved in THF and subsequently added dropwise into deionic water to form micelles aggregation. The mixtures were then dialyzed against deionic water to remove the residual THF. The obtained micelles solutions were diluted to a concentration of 1.0 mg.mL -1 . The average hydrodynamic diameters for MPEG-b-PTAm and MPEG-b-PLA-b-PTAm micelles were characterized by DLS to be 48 nm and 58 nm (see Figure 6.5 C), respectively. The slightly increased size of the micelles prepared from MPEG-b-PLA-b-PTAm may be ascribed to the more hydrophobic molecular weight ratio of MPEG-b-PLA-b-PTAm compared to that of MPEG-b-PTAm. 21 TEM was also used to confirm the micelles structure of the two block copolymers as shown in Figure 6.5 A and B. Cyclic voltammograms of MPEG-b-PTAm and MPEG-b-PLA-b-PTAm micelles were also conducted in aqueous HCl solution at a scanning rate of 10 mV/min. The results showed in Figure 6.6 demonstrated that both of the micelles produced a reversible redox wave at around 0.7 V vs Ag/AgCl, indicating that the nitroxyl radicals had been successfully incorporated into the micelles. Figure 6.5 TEM and DLS characterizations of MPEG-b-PTAm micelles (A) and MPEG-b-PLA-b-PTAm micelles (B) ‐ 119 ‐
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Catalytic Synthesis and Characteriz
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Preface Biodegradable polyesters ha
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Chapter 3 Polymerization of Lactic
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Chapter 1 Polymerization and Applic
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- 3 - Polymerization and Applicatio
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1.2.2 Aluminum Catalysts - 7 - Poly
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1.3 Polylactide 1.3.1 Introduction
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- 13 - Polymerization and Applicati
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1.3.4 Application of PLA Figure 1.3
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1.5.1.4 Polyaniline (PANi) - 21 - P
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1.6.1 Radical Polymers for Organic
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initialization of the device by app
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1.6.2.4 Others - 49 - Polymerizatio
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182. R. B. Weller, J. Invest. Derma
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Chapter 2 Synthesis and Electrochem
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Synthesis and Electrochemistry of S
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Page 77 and 78: Synthesis and Electrochemistry of S
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Page 84 and 85: Chapter 3 3.1 Introduction Poly(lac
Page 86 and 87: Chapter 3 polydispersity index (PDI
Page 88 and 89: Chapter 3 aluminum based complexes
Page 90 and 91: Chapter 3 3.5 Conclusions Co(III) c
Page 92 and 93: Chapter 3 22. Z. H. Tang, X. S. Che
Page 94 and 95: Chapter 4 4.1 Introduction Stimulus
Page 96 and 97: Chapter 4 the proton of methenyl gr
Page 98 and 99: Chapter 4 attributed to the amide g
Page 100 and 101: Chapter 4 4.4 Thermal Properties Th
Page 102 and 103: Chapter 4 Figure 4.8 MTT assay for
Page 104 and 105: Chapter 4 The 1 H NMR and 13 C NMR
Page 106 and 107: Chapter 4 Cell viability (%) = (Asa
Page 109 and 110: Chapter 5 Synthesis of Triblock Cop
Page 111 and 112: 5.2 Synthesis of Triblock Copolymer
Page 113 and 114: Sample Table 1. Feed and result com
Page 115 and 116: = 25 μm. B: MTT assay for the cyto
Page 117 and 118: ‐ 109 ‐ Synthesis of Triblock C
Page 119: ‐ 111 ‐ Synthesis of Triblock C
Page 124 and 125: Chapter 6 6.1 Introduction Since th
Page 126 and 127: Chapter 6 6.3 Synthesis of MPEG-b-P
Page 130 and 131: Chapter 6 Figure 6.6 Cyclic voltamm
Page 132 and 133: Chapter 6 vivo cytotoxicity was als
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Page 136 and 137: Chapter 6 CO2 for 24 h. RSC96 cells
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Page 147 and 148: 13. Xuan Pang, Xuesi Chen, Xiuli Zh
Page 149: Acknowledgments The present thesis
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