New Directions In STD Treatment - University of Hawaii

New Directions In STD Treatment - University of Hawaii New Directions In STD Treatment - University of Hawaii

16.01.2013 Views

Bacterial Vaginosis – TreatmentTreatment: Issues � Clindamycin cream may be less effective than metronidazole � DELETED metronidazole 2 g single dose alternative � Suppressive treatment: � ADDED metronidazole gel twice weekly � Treatment of BV in pregnancy: � Metronidazole 500 mg po BID in addition to 250 mg po TID � Pre-surgical screening and treatment � Benefit for hysterectomy and surgical abortion � Consider for other procedures

BV Treatment Recommended regimens: � Metronidazole 500 mg PO BID x 7 d * � Metronidazole gel 0.75% 5 g per vagina QD/BID x 5 d � Clindamycin cream 2% 5 g per vagina QHS x 7 d Alternative regimens: � Clindamycin 300 mg PO BID x 7 d � Clindamycin ovules 100 mg per vagina QHS x 3 d Recommended regimens in pregnancy: � Metronidazole 500 mg PO BID x 7 days � Metronidazole 250 mg PO TID x 7 days � Clindamycin 300 mg PO BID x 7 days Suppressive treatment: � Metronidazole gel 0.75% twice weekly for 6 * months Preferred

Bacterial Vaginosis – <strong>Treatment</strong><br />

� <strong>Treatment</strong>:<br />

Issues<br />

� Clindamycin cream may be less effective than<br />

metronidazole<br />

� DELETED metronidazole 2 g single dose alternative<br />

� Suppressive treatment:<br />

� ADDED metronidazole gel twice weekly<br />

� <strong>Treatment</strong> <strong>of</strong> BV in pregnancy:<br />

� Metronidazole 500 mg po BID in addition to 250 mg po<br />

TID<br />

� Pre-surgical screening and treatment<br />

� Benefit for hysterectomy and surgical abortion<br />

� Consider for other procedures

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