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New Directions In STD Treatment - University of Hawaii

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Issues Regarding Anal Cancer Screening in<br />

MSM or HIV-infected patients<br />

� Anal HPV DNA is prevalent so role <strong>of</strong> HPV testing in<br />

anal cancer screening is unclear<br />

� Little data on the natural history <strong>of</strong> anal SILs<br />

� Questions regarding reliability <strong>of</strong> screening methods<br />

� <strong>In</strong>consistent correlation between anal Paps and histology<br />

� <strong>In</strong>traobserver variability in interpretation <strong>of</strong> anal Pap smears<br />

� Limited data on treatment efficacy and side effects<br />

� If clinicians are conducting anal cancer screening, then<br />

collecting useful data to inform screening<br />

recommendations is recommended

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