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New Directions In STD Treatment - University of Hawaii

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Syphilis Issues<br />

� Diagnostic issues<br />

� Criteria for diagnosing early latent is change to be<br />

consistent with the surveillance case definition<br />

� <strong>New</strong> EIA testing algorithms:<br />

� reflexive quantitative RPR/VDRL<br />

� alternative treponemal test for discrepancies<br />

� FP in low risk populations<br />

� Some experts recommend CSF exam for<br />

� All patients with latent syphilis and RPR ≥ 1:32<br />

� HIV-infected patients with latent syphilis and CD4 count ≤<br />

350<br />

� Recommend against the use <strong>of</strong> azithromycin<br />

� Note penicillin usage problems<br />

� BIC shortage<br />

� Specify use <strong>of</strong> Bicillin L-A (NOT Bicillin C-R)

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