Priv.-Doz. Dr. med. Dipl. Phys. Rotraut Mößner
Priv.-Doz. Dr. med. Dipl. Phys. Rotraut Mößner
Priv.-Doz. Dr. med. Dipl. Phys. Rotraut Mößner
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<strong>Priv</strong>.-<strong>Doz</strong>. <strong>Dr</strong>. <strong>med</strong>. <strong>Dipl</strong>. <strong>Phys</strong>. <strong>Rotraut</strong> <strong>Mößner</strong><br />
Klinische Tätigkeit: Leiterin der Spezialsprechstunde für Psoriasis und Psoriasisarthritis<br />
Klinische Studien bei der Psoriasis<br />
Allgemeine Ambulanz<br />
Sonographie der Haut<br />
Phlebologie<br />
Weitere Tätigkeiten: Leiterin des Mykologischen Labors<br />
Forschungsschwerpunkt: Systemtherapeutika bei der Psoriasis<br />
Genetische Grundlagen der Psoriasis<br />
PPARgamma Agonisten beim Malignen Melanom<br />
Genetische Grundlagen des Malignen Melanoms<br />
Ausgewählte Publikationen: Psoriasis und Autoimmunerkrankungen<br />
1. Mössner R, Schön MP, Reich K: TNF-antagonists in the therapy of<br />
psoriasis. Clinics in Dermatology (im <strong>Dr</strong>uck)<br />
2. Kingo K, Mössner R, Rätsep R, Raud K, Krüger U, Silm H, Vasar E,<br />
Reich K, Koks S. Association analysis of IL20RA and IL20RB genes in<br />
psoriasis. Genes Immun (im <strong>Dr</strong>uck)<br />
3. Mössner R, Thaci D, Mohr J, Paetzold S, Bertsch HP, Krüger U, Reich<br />
K. Manifestation of palmoplantar pustulosis during or after infliximab<br />
therapy for plaque-type psoriasis – report of 5 cases. Archives Derm<br />
Res (im <strong>Dr</strong>uck)<br />
4. Radtke MA, Mössner R, Augustin M, Reich K: Psoriasis-Arthritis -<br />
Therapeutische Strategien: je früher desto besser. Der Deutsche<br />
Dermatologe 6:1-4 (2007)<br />
5. Radtke MA, Mössner R, Augustin M, Reich K: Psoriasis Arthritis: Klinik,<br />
Pathogenese und Diagnostik. Der Deutsche Dermatologe 5:2-8 (2007)<br />
6. Kingo K, Mössner R, Kõks S, Rätsep R, Krüger U, Vasar E, Reich K,<br />
Silm H. Association analysis of IL19, IL20 and IL24 genes in<br />
palmoplantar pustulosis. BJD 156: 646-52 (2007)<br />
7. Mössner R, Reich K: Biologics in der Therapie der Psoriasis –<br />
unerwünschte Effekte an der Haut. Allergo Journal 15: 492-500 (2006)<br />
8. Mössner R, Reich K: Infliximab in the treatment of psoriasis. Expert<br />
Rev Dermatol 1: 515-26 (2006)<br />
9. Mössner R, Kingo K, König IR, Krüger U, Ziegler U, Neumann Ch, Silm<br />
H, Westphal GA, Reich K: Association of TNFA–238 and –308 promoter<br />
polymorphisms with psoriasis vulgaris but not with pustulosis<br />
palmoplantaris in an Estonian population. J Invest Dermatol 124: 282-4<br />
(2005)<br />
10. Mössner R, Reich K: Pathogenetische Aspekte der Psoriasis-Arthritis.<br />
Haut 1: 19-24 (2005)<br />
11. Mössner R, Reich K: Infliximab: Stellenwert in der Therapie der<br />
Psoriasis. Hautarzt 56: 831-8 (2005)<br />
12. Mössner R, Kaiser R, Matern P, Krüger U, Westphal GA, Brockmöller<br />
J, Ziegler A, Neumann Ch, König I, Reich K: Variations in the genes<br />
encoding the peroxisome proliferator-activated receptors a and g in<br />
psoriasis. Arch Dermatol Res 296: 1-5 (2004)
13. Mössner R, Tings T, Beckmann I, Neumann Ch, Paulus W, Reich K. A<br />
close-up look at autoimmune muscle disorders: Association of Lambert-<br />
Eaton myasthenic syndrome with dermatomyositis. Scand J Rheum 33:<br />
271-5 (2004)<br />
14. Mössner R, Beckmann I, Hallermann C, Neumann Ch, Reich K:<br />
Granulocyte colony-stimulating factor (G-CSF)-induced psoriasiform<br />
dermatitis resembles psoriasis with regard to abnormal cytokine<br />
expression and epidermal activation. Exp Dermatol 13: 340-6 (2004)<br />
15. Reich K, Mössner R, König IR, Westphal GA, Ziegler A, Neumann Ch:<br />
Promoter polymorphisms of the genes encoding tumor necrosis factoralpha<br />
and interleukin-1beta are associated with different subtypes of<br />
psoriasis characterized by early and late disease onset. J Invest<br />
Dermatol 118: 155-63 (2002)<br />
16. Reich K, Hummel KM, Beckmann I, Mössner R, Neumann Ch:<br />
Treatment of severe psoriasis and psoriatic arthritis with leflunomide. Br<br />
J Dermatol 146: 335-336 (2002)<br />
Neurodermitis und Kontaktekzem<br />
1. Reich K, Westphal G, König IR, Mössner R, Krüger U, Ziegler A,<br />
Neumann Ch , Schnuch A. Association of allergic contact dermatitis with<br />
a promoter polymorphism in the IL16 gene. J Allergy Clin Immunol. 112:<br />
1191-4 (2003)<br />
2. Westphal GA, Schnuch A, Mössner R, König IR, Kränke B, Hallier E,<br />
Ziegler A, Reich K. Cytokine gene polymorphisms in allergic contact<br />
dermatitis. Contact Dermatitis 48: 93-8 (2003)<br />
3. Jung Th, Mössner R, Neumann C. Naïve CD4+ T cells from patients<br />
with atopic dermatitis show an aberrant maturation towards IL-4producing<br />
skin-homing CLA+ cells. Exp Dermatol 12: 555-62 (2003)<br />
4. Reich K, Westphal GA, König IR, Mössner R, Schupp P, Gutgesell C,<br />
Hallier E, Ziegler A, Neumann Ch. Cytokine gene polymorphisms in<br />
atopic dermatitis. Br J Dermatol. 148: 1237-41 (2003)<br />
5. Jung Th, Mössner R, Dieckhoff K, Heidrich S, Neumann Ch.<br />
Mechanisms of deficient IFN-g production in atopic diseases. IFN-g<br />
production by CD4+ effector T cells generated from naive precursors is<br />
restored by priming in the presence of high doses of IL-2 or IL-12.<br />
Clinical Experimental Allergy 29: 912-919 (1999)<br />
Melanom<br />
1. Mössner R, Anders N, König IR, Krüger U, Schmidt D, Berking C,<br />
Ziegler A, Brockmöller J, Kaiser R, Volkenandt M, Westphal GA, Reich<br />
K. Variations of the melanocortin-1 receptor and the glutathione-S<br />
transferase T1 and M1 genes in cutaneous malignant melanoma. Arch<br />
Dermatol Res 298: 371-9 (2007)<br />
2. Mössner R, Schulz U, Krüger U, Middel P, Schinner S, Füzesi L,<br />
Neumann Ch, Reich K. Agonists of peroxisome proliferator-activated<br />
receptor gamma inhibit cell growth in malignant melanoma. J Invest<br />
Dermatol 119: 576-82 (2002)<br />
3. Mössner R, Jankowski F, König IR, Krüger U, Anders N, Westphal G,<br />
Berking C, Brockmöller J, Ziegler A, Kaiser R, Volkenandt M, Reich K.<br />
Variations in the peroxisome proliferator-activated receptor-gamma<br />
gene and melanoma risk. Cancer Letters 246: 218-23 (2007)
Signaltransduktion<br />
1. Gillis KD, Mössner R, Neher E. Protein kinase C enhances exocytosis<br />
from chromaffin cells by increasing the size of the readily releasable<br />
pool of secretory granules. Neuron 16: 1209-1220 (1996)