The Mitochondrial Free Radical Theory of Aging - Supernova: Pliki
The Mitochondrial Free Radical Theory of Aging - Supernova: Pliki The Mitochondrial Free Radical Theory of Aging - Supernova: Pliki
Some Testable Predictions of MiFRA 8. Gross NJ, Getz GS, Rabinowitz M. Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat. J Biol Chem 1969; 244:1552-1562. 9. Menzies RA, Gold PH. The turnover of mitochondria in a variety of tissues of young adult and aged rats. J Biol Chem 1971; 246:2425-2429. 10. Wang GJ, Nutter LM, Thayer SA. Insensitivity of cultured rat cortical neurons to mitochondrial DNA synthesis inhibitors: Evidence for a slow turnover of mitochondrial DNA. Biochem Pharmacol 1997; 54:181-187. 11. Chambers P, Gingold E. A direct study of the relative synthesis of petite and grande mitochondrial DNA in zygotes from crosses involving suppressive petite mutants of Saccharomyces cerevisiae. Curr Genet 1986; 10:565-571. 12. King MP. Transmitochondrial cells in the study of mitochondrial disease. Molec Genet Metab 1998; 63:43. 13. Goldenberg H, Crane FL, Morre DJ. NADH oxidoreductase of mouse liver plasma membranes. J Biol Chem 1979; 254:2491-2498. 14. Oldfors A, Larsson NG, Holme E et al. Mitochondrial DNA deletions and cytochrome c oxidase deficiency in muscle fibres. J Neurol Sci 1992; 110:169-177. 15. Aspnes LE, Lee CM, Weindruch R et al. Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle. FASEB J 1997; 11:573-581. 16. Lee CM, Lopez ME, Weindruch R et al. Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy. Free Radic Biol Med 1998; 25:964-972. 17. Pearson AGE. Histochemistry: theoretical and applied. 2nd ed. London: Churchill, 1961. 18. Nishinaka Y, Aramaki Y, Yoshida H et al. A new sensitive chemiluminescence probe, L-012, for measuring the production of superoxide anion by cells. Biochem Biophys Res Commun 1993; 193:554-559. 19. Fridovich I. Superoxide anion radical (O2 — ), superoxide dismutases, and related matters. J Biol Chem 1997; 272:18515-18517. 20. Larm JA, Wolvetang EJ, Vaillant F et al. Increase of plasma-membrane oxidoreductase activity is not correlated with the production of extracellular superoxide radicals in human Namalwa cells. Protoplasma 1995; 184:173-180. 21. Clark MG, Partick EJ, Patten GS et al. Evidence for the extracellular reduction of ferricyanide by rat liver. A trans-plasma membrane redox system. Biochem J 1981; 200:565-572. 22. a)Karlsson K, Marklund SL. Heparin-induced release of extracellular superoxide dismutase to human blood plasma. Biochem J 1987; 242:55-59. 22. b)Frederiks WM, Bosch KS. Localization of superoxide dismutase activity in rat tissues. Free Radic Biol Med 1997; 22:241-248. 23. Larm JA, Vaillant F, Linnane AW et al. Up-regulation of the plasma membrane oxidoreductase as a prerequisite for the viability of human Namalwa ρ 0 cells. J Biol Chem 1994; 269:30097-30100. 24. Steinbrecher UP, Parthasarathy S, Leake DS et al. Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Proc Natl Acad Sci USA 1984; 81:3883-3887. 25. Bilheimer DW, Grundy SM, Brown MS et al. Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes. Proc Natl Acad Sci USA 1983; 80:4124-4128. 26. Boveris A, Chance B. The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 1973; 134:707-716. 27. Kappus H. Lipid peroxidation: Mechanisms, analysis, enzymology and biological relevance. In: Sies H, ed. Oxidative Stress. London: Academic Press, Inc., 1985:273-310. 28. Berlett BS, Stadtman ER. Protein oxidation in aging, disease, and oxidative stress. J Biol Chem 1997; 272:20313-20316. 29. Tsuneki K, Ouji M, Saito H. Seasonal migration and gonadal changes in the hagfish Eptatretus burgeri. Jpn J Ichthyol 1983; 29:429-440. 30. Patnaik BK. Ageing in reptiles. Gerontology 1994; 40:200-220. 31. Patnaik BK, Mahapatro N, Jena BS. Ageing in fishes. Gerontology 1994; 40:113-132. 163
164 The Mitochondrial Free Radical Theory of Aging 32. Benoit PW, Belt WD. Destruction and regeneration of skeletal muscle after treatment with a local anaesthetic, bupivacaine (Marcaine). J Anat 1970; 107:547-556. 33. Lexell JG. Human aging, muscle mass, and fiber type composition. J Gerontol 1995; 50A (Spec. Issue):11-16. 34. Kara TC. Ageing in amphibians. Gerontology 1994; 40:161-173.
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164<br />
<strong>The</strong> <strong>Mitochondrial</strong> <strong>Free</strong> <strong>Radical</strong> <strong>The</strong>ory <strong>of</strong> <strong>Aging</strong><br />
32. Benoit PW, Belt WD. Destruction and regeneration <strong>of</strong> skeletal muscle after treatment with<br />
a local anaesthetic, bupivacaine (Marcaine). J Anat 1970; 107:547-556.<br />
33. Lexell JG. Human aging, muscle mass, and fiber type composition. J Gerontol 1995; 50A<br />
(Spec. Issue):11-16.<br />
34. Kara TC. Ageing in amphibians. Gerontology 1994; 40:161-173.