The Mitochondrial Free Radical Theory of Aging - Supernova: Pliki

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128 Fig. 10.2. Selection for fusion causes selection for recombination. The Mitochondrial Free Radical Theory of Aging
Frequently-Asked Questions Fig. 10.2., cont. See opposite page longer anaerobic muscle fiber segments than young ones, suggesting that an affected fiber can last arbitrarily long while the defect slowly propagates along it. 50b,50c 10.10. What About in Situ Membrane Repair? In principle, one can imagine enzymatic systems which remove oxidatively damaged molecules from membranes and replace them with pristine ones. In practice, as it happens, such systems do indeed exist. An enzyme which attacks a phospholipid is (naturally) called a phospholipase, and many are known; the one of most interest in this context is called phospholipase A2. It detaches one of the fatty acid side chains of a phospholipid. (Other 129
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COMPANY de Grey The Mitochondrial F
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ISBN: 1-57059-564-X MOLECULAR BIOLO
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7. The Status of Gerontological The
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17. Conclusion: The Role of the Ger
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I cannot overstate my profound grat
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CHAPTER 1 Introduction 1.1. What Is
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Introduction Some may feel that all
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6 The Mitochondrial Free Radical Th
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8 The Mitochondrial Free Radical Th
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10 The Mitochondrial Free Radical T
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18 Fig. 2.7. The respiratory chain.
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24 Fig. 2.9. Types of protein impor
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26 Fig. 2.10. Why the DNA bases pai
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CHAPTER 3 An Introduction to Free R
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An Introduction to Free Radicals Ta
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An Introduction to Free Radicals Fi
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An Introduction to Free Radicals Re
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CHAPTER 6 History of the Mitochondr
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History of the Mitochondrial Free R
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Page 97 and 98: CHAPTER 8 The Search for How Mutant
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Page 107 and 108: CHAPTER 9 The Search for How So Few
Page 109 and 110: The Search for How So Few Anaerobic
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Page 145 and 146: CHAPTER 11 A Challenge from Textboo
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Page 177 and 178: CHAPTER 14 Ablation of Anaerobic Ce
Page 179 and 180: Ablation of Anaerobic Cells: Techni
Page 181 and 182: CHAPTER 15 Transgenic Copies of mtD
Page 183 and 184: Transgenic Copies of mtDNA: Techniq
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Transgenic Copies of mtDNA: Techniq
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CHAPTER 16 Prospective Impact on th
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Prospective Impact on the Healthy H
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Prospective Impact on the Healthy H
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196 The Mitochondrial Free Radical
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198 The Mitochondrial Free Radical
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Index Symbols “~”, 19 A Acetald
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Index Copper 35, 107 see also trans
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Index Heart comparison to man-made
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Index genetic code 23, 115-118, 177
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Index Perhydroxyl radical 41, 122,
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Index protonation see protonation (
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MOLECULAR BIOLOGY INTELLIGENCE UNIT
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