Regulation of the dopamine transporter - Addiction Research ...

DAT Regulation Schmitt & Reith
48. Gorentla, B.K. & R.A. Vaughan. 2005. Differential effects
of dopamine and psychoactive drugs on dopamine
transporter phosphorylation and regulation. Neuropharmacology
49: 759–768.
49. Vaughan, R.A. 2004. Phosphorylation and regulation
of psychostimulant-sensitive neurotransmitter transporters.
J. Pharmacol. Exp. Ther. 310: 1–7.
50. Melikian, H.E. 2004. Neurotransmitter transporter
trafficking: endocytosis, recycling, and regulation.
Pharmacol. Ther. 104: 17–27.
51. Foster, J.D., M.A. Cervinski, B.K. Gorentla & R.A.
Vaughan. 2006. Regulation of the dopamine transporter
by phosphorylation. Handbook Exp. Pharmacol. 175:
197–214.
52. Hoover, B.R., C.V. Everett, A. Sorkin & N.R. Zahniser.
2007. Rapid regulation of dopamine transporters by
tyrosine kinases in rat neuronal preparations. J. Neurochem.
101: 1258–1271.
53. Vaughan, R.A., R.A. Huff, G.R. Uhl & M.J. Kuhar. 1997.
Protein kinase C–mediated phosphorylation and functional
regulation of dopamine transporters in striatal
synaptosomes. J. Biol. Chem. 272: 15541–15546.
54. Huff, R.A., R.A. Vaughan, M.J. Kuhar & G.R. Uhl.
1997. Phorbol esters increase dopamine transporter
phosphorylation and decrease transport Vmax. J. Neurochem.
68: 225–232.
55. Zhu, S.J., M.P. Kavanaugh, M.S. Sonders, et al. 1997.
Activation of protein kinase C inhibits uptake, currents
and binding associated with the human dopamine
transporter expressed in Xenopus oocytes. J. Pharmacol.
Exp. Ther. 282: 1358–1365.
56. Melikian, H.E. & K.M. Buckley. 1999. Membrane trafficking
regulates the activity of the human dopamine
transporter. J. Neurosci. 19: 7699–7710.
57. Daniels, G.M. & S.G. Amara. 1999. Regulated trafficking
of the human dopamine transporter. Clathrinmediated
internalization and lysosomal degradation in
response to phorbol esters. J. Biol. Chem. 274: 35794–
35801.
58. Loder, M.K. & H.E. Melikian. 2003. The dopamine
transporter constitutively internalizes and recycles in
a protein kinase C-regulated manner in stably transfected
PC12 cell lines. J. Biol. Chem. 278: 22168–
22174.
59. Foster, J.D., B. Pananusorn & R.A. Vaughan. 2002.
Dopamine transporters are phosphorylated on Nterminal
serines in rat striatum. J. Biol. Chem. 277:
25178–25186.
60. Holton, K.L., M.K. Loder & H.E. Melikian. 2005. Nonclassical,
distinct endocytic signals dictate constitutive
and PKC-regulated neurotransmitter transporter internalization.
Nat. Neurosci. 8: 881–888.
61. Foster, J.D., S.D. Adkins, J.R. Lever & R.A. Vaughan.
2008. Phorbol ester induced trafficking-independent
regulation and enhanced phosphorylation of the
dopamine transporter associated with membrane
rafts and cholesterol. J. Neurochem. 105: 1683–
1699.
62. Chang, M.Y., S.H. Lee, J.H. Kim, et al. 2001. Protein
kinase C-mediated functional regulation of dopamine
transporter is not achieved by direct phosphorylation
of the dopamine transporter protein. J. Neurochem. 77:
754–761.
63. Granäs,C.,J.Ferrer,C.J.Loland,et al. 2003. N-terminal
truncation of the dopamine transporter abolishes phorbol
ester- and substance P receptor-stimulated phosphorylation
without impairing transporter internalization.
J. Biol. Chem. 278: 4990–5000.
64. Sung, U., S. Apparsundaram, A. Galli, et al. 2003.
A regulated interaction of syntaxin 1A with the
antidepressant-sensitive norepinephrine transporter
establishes catecholamine clearance capacity. J. Neurosci.
23: 1697–1709.
65. Dipace, C., U. Sung, F. Binda, et al. 2007. Amphetamine
induces a calcium/calmodulin-dependent protein kinase
II-dependent reduction in norepinephrine transporter
surface expression linked to changes in syntaxin
1A/transporter complexes. Mol. Pharmacol. 71: 230–
239.
66. Lee, K.H., M.Y. Kim, D.H. Kim & Y.S. Lee. 2004. Syntaxin
1A and receptor for activated C kinase interact
with the N-terminal region of human dopamine transporter.
Neurochem. Res. 29: 1405–1409.
67. Binda, F., C. Dipace, E. Bowton, et al. 2008. Syntaxin 1A
interaction with the dopamine transporter promotes
amphetamine-induced dopamine efflux. Mol. Pharmacol.
74: 1101–1108.
68. Johnson, L.A., B. Guptaroy, D. Lund, et al. 2005. Regulation
of amphetamine-stimulated dopamine efflux by
protein kinase C beta. J. Biol. Chem. 280: 10914–10919.
69. Khoshbouei, H., N. Sen, B. Guptaroy, et al. 2004. Nterminal
phosphorylation of the dopamine transporter
is required for amphetamine-induced efflux. PLoS Biol.
2: 387–393.
70. Sorkina, T., T.L. Richards, A. Rao, et al. 2009. Negative
regulation of dopamine transporter endocytosis by
membrane-proximal N-terminal residues. J. Neurosci.
29: 1361–1374.
71. Zhang, L. & M.E. Reith. 1996. Regulation of the functional
activity of the human dopamine transporter by
336 Ann. N.Y. Acad. Sci. 1187 (2010) 316–340 c○ 2010 New York Academy of Sciences.