1 BETA-CELL FAILURE IN DIABETES AND PRESERVATION BY ...
1 BETA-CELL FAILURE IN DIABETES AND PRESERVATION BY ...
1 BETA-CELL FAILURE IN DIABETES AND PRESERVATION BY ...
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
16<br />
183. Farilla L,Hui H,Bertolloto C ,Kang E,Bulotta A,Di Mario U,Perfetti R 2002<br />
Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker<br />
diabetic rats. Endocrinology 143:4397-4408.<br />
184. Hui H,Nourparvar A,Zhao X,Perfetti R. 2003 Glucagon-like peptide-1 inhibits<br />
apoptosis of insulin-secreting cells via a cyclic 5`-adenosine monophosphate-dependent<br />
protein-kinase-A and a phosphatidylinositol 3-kinase–dependent pathway .Endocrinology<br />
144:1444-1455.<br />
185. Xu G,Stoffers DA,Habener JF,Bonner-Weir S 1999 Exendin-4 stimulates both<br />
beta-cell replication and neogenesis,resulting in increased beta-cell mass and improved<br />
glucose tolerance in diabetic rats. Diabetes 48:2270-2276.147<br />
186. Perfetti R,Zhou J,Doyle ME,Egan JM 2000 GLP-1 induces cell proliferation,PDX-1<br />
expression and increases endocrine cell mass in the pancreas of old ,glucose-intolerant rats.<br />
Endocrinology 141:4600-4605.<br />
187. Perfetti R 2004 The role of GLP-1 in the regulation of islet cell mass Medscape<br />
Diabetes & Endocrinology 6(1).<br />
188. Hiles R,Carpenter T,Serota D,Schafer K,Ross P,Nelson D,Rebellato M 2004<br />
Exenatide does not cause pancreatic islet cell proliferative lesions in rats and mice<br />
following 2-year exposure [Abstract 1585-P] Diabetes (Suppl 2):A380.<br />
189. Bahnsali A 2006 GLP-1 Overview .In :International Investigator`s Meeting of the<br />
Clinical study NN 2211-1697(Liraglutide).in Zurich,Switzerland,April 21.<br />
190. Li Y,Hansotia Y,Yusta B,Ris F,Halban PA,Drucker DJ 2003 Glucagon-like peptide-<br />
1 receptor signaling modulates beta-cell apoptosis. J Biiol Chem 278:471-478.<br />
191. Koehler JA,Drucker DJ 2006 Activation of Glucagon-like peptide-1 Receptor<br />
signaling does not modify the growth or apoptosis of human pancreatic cancer cells<br />
Diabetes 55:1369-1379.<br />
192. Poffenberger G,Chen Z,Liu E,Drucker DJ,Harlan DM,Aramandla R,Brissova<br />
M,Powers AC 2006 Exendin-4(Ex-4) improves survival and function of intra-hepatic<br />
human and non-human primate islet transplants[Abstract 262-OR]. Diabetes 56(Suppl<br />
1)A61<br />
193. Sturis J.Gotfredsen CF,Romer J,Rolin B,Ribel U,Brand CL,Wilken M,Wassermann<br />
K,Deacon CF,Carr RD,Knudsen LB 2003 GLP-1 derivative liraglutide in rats with betacell<br />
deficiencies : influence of metabolic state on beta-cell dynamics Br J Pharmacol<br />
140:123-132.<br />
194. Bregenholt S, Moldrup A,Blume N,Karlsen AE,Nissen Friedrichsen B,Tornhave<br />
D,Knudsen LB,Petersen JS 2005 The long-acting glucagon-like peptide-1 analogue