omation mbers - Society for Laboratory Automation and Screening

10:30 am – 12:00 pm Room A2 ADME – Tox
Chair: Elizabeth Everitt, Abbott Laboratories
10:30 am Role of Automated High Throughout Nephelometric Aqueous Solubility System in
Early Drug Discovery; Arun Mandagere, Pfizer Global R&D
11:00 am Higher Throughput Strategies for Support of Early ADME In-vitro Screening;
Ken Matuszak, Abbott Laboratories
11:30 am The Role of Genomics in Toxicology; Alexandra Heinloth, NIEHS
10:30 am – 12:00 pm Room A4 Microfluidics Bioanalytical
Chair: Laurie Locascio, National Institute of Standards and Technology
10:30 am An Autonomous PCR-based Air Monitoring System to Detect and Identify Infectious Agents;
Phillip Belgrader, Microfluidic Systems, Inc.
11:00 am Protein Sizing and Relative Quantitation Determination Using a Microfluidic LabChip ® Device;
Adrian Winoto, Caliper Technologies Corp.
11:30 am Using Liposomes for High-Efficiency Mixing in Microfluidic Systems;
Laurie Locascio, National Institute of Standards and Technology
10:30 am – 12:00 pm Room B1 Proteomics Technology 3
Chair: Joseph Loo, University of California, Los Angeles
10:30 am Sample Preparation Tips for Sample Enrichment and Direct Elution Nanoelectrospray
Mass Spectrometry Analysis for Enhanced Sensitivity for Protein Characterization;
Gary Schultz, Advion BioSciences, Inc.
11:00 am Progress in Automating Top Down Proteomics; Neil Kelleher, University of Illinois
11:30 am A View of the Proteome Provided by New Mass Spectrometry Technologies;
Joseph Loo, University of California, Los Angeles
10:30 am – 12:00 pm Room A1 Genomics Advanced Topics
Chair: Gary Nunn, Applied Biosystem
10:30 am Increasing Instrumentation Availability by Using Reliability Centered Maintenance (RCM)
Principles and Applying Them to Production Line Instrumentation at the DOE Joint Genome
Institute; Simon Roberts, DOE Joint Genome Institute
11:00 am Evaluation of High Throughput SNP Genotyping Lab Data Using FOCUS Statistical Software;
Sheri Olson, Applied Biosystem
11:30 am Future Clinical Analysis: Component Based Framework for Modular Hardware and Software
Integration of Different Clinical Equipment; Ralf Muckenhirn, Fraunhofer IPA
10:30 am – 12:00 pm Room C1 Clinical Arrays
Chair: William Wachsman, University of California, San Diego
10:30 am Using Reference Gene Expression Datasets to Make Sense of Your Array Data;
John Walker, GNF
11:00 am Molecular Tools Designed for the Clinic; John Palma, Affymetrix, Inc.
11:30 am Clinical Validation of the Affymetrix Microarray and the Challenges Faced;
Richard Hockett, Eli Lilly and Company
10:30 am – 12:00 pm Room A3 Emerging IT Informatics
Chair: Jay Gill, Bristol-Myers Squibb Co.
10:30 am Design Tools: New Approach to Computing in Life Sciences; Larry Arnstein, Teranode Corporation
11:00 am Python for Scientific Computing – An Open Source Solution; Eric Jones, Enthought, Inc.
11:30 am Universal and Mobile Messaging Framework M2A “Message to Anywhere” for Laboratory
Automation; Gerald Knoll, Fraunhofer Institute Manufacturing Engineering and Automation (IPA)
12:00 – 1:30 pm Lunch Break
1:30 – 3:30 pm Room B1 Drug Discovery Case Studies
Chair: Jürgen Drews, Nigeons GmbH
1:30 pm Hit and Lead Generation Beyond High Throughput Screening;
Alexander Alanine, F. Hoffmann-La Roche Ltd
2:00 pm Alliances in Technology; Esteban Pombo-Villar, Novartis Pharma Ltd.
2:30 pm Understanding Risk and Value: Decision Gates in Drug Development;
Fred Pritchard, MDS Pharma Services
3:00 pm Drug Prototypes – What We Learn From History;
Walter Sneader, Strathclyde Institute for Biomedical Science
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PROGRAM