omation mbers - Society for Laboratory Automation and Screening
omation mbers - Society for Laboratory Automation and Screening
omation mbers - Society for Laboratory Automation and Screening
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TP035<br />
Thomas Friedl<strong>and</strong>er<br />
Foster-Miller, Inc.<br />
350 Second Avenue<br />
Waltham, Massachusetts 02451-1196<br />
tfriedl<strong>and</strong>er@foster-miller.com<br />
Microfluidics Impact on Lab Aut<strong>omation</strong> <strong>and</strong> HTS<br />
We will look at the current technologies being developed in the world of microfluidics (Lab-On-a-Chip or LOC) <strong>and</strong><br />
discuss the areas they will impact in the macro world of Lab Aut<strong>omation</strong> <strong>and</strong> HTS. Some HTS applications may be<br />
completely replaced by new developments while others may benefit <strong>and</strong> be helped along by increased screening<br />
capabilities presented by LOC solutions. We will identify how Lab Aut<strong>omation</strong> groups can help bring this new<br />
technology to their in-house customer base <strong>and</strong> help provide support <strong>and</strong> integration with current HTS solutions<br />
already in place. We will also discuss the broad nature of microfluidics R&D <strong>and</strong> the skill sets required to bring this<br />
new technology to the <strong>for</strong>efront. The discussion will include macromolecular crystallization technologies, HPLC,<br />
Genotyping, genetics, proteomics, cell based assays, proteins, labeling among other topics.<br />
TP036<br />
Sean Gallagher<br />
UVP, Inc.<br />
Product <strong>and</strong> Applications Development<br />
2066 W. 11th Street<br />
Upl<strong>and</strong>, Cali<strong>for</strong>nia 91786<br />
seang@uvp.com<br />
Co-Author(s)<br />
Alex Waluszko, Hui Zhang, John Wallace, <strong>and</strong> Kate Cole,<br />
UVP, Inc.<br />
163<br />
Molli Osburn, Scripps College<br />
Applications of a Highly Uni<strong>for</strong>m UV Transillumination Imaging System <strong>for</strong> Quantitative DNA<br />
<strong>and</strong> Protein Analysis<br />
UV transillumination is a ubiquitous tool in Life Science research. With few exceptions, fluorescent stains used<br />
in post electrophoresis analysis of proteins <strong>and</strong> nucleic acids have significant excitation peaks with ultraviolet<br />
(300-365 nm) light, making midrange UV the excitation source of choice <strong>for</strong> high sensitivity analysis <strong>for</strong> many<br />
fluorophores. However, quantitative analysis is limited by the extreme lack of illumination uni<strong>for</strong>mity across the<br />
surface of typical UV light boxes. We report the development of a highly uni<strong>for</strong>m UV transillumination system.<br />
Through use of a high density lighting system with a tuned phosphor coating, uni<strong>for</strong>mity of
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