omation mbers - Society for Laboratory Automation and Screening
omation mbers - Society for Laboratory Automation and Screening
omation mbers - Society for Laboratory Automation and Screening
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12:00 pm Wednesday, February 4 Emerging Technologies – Hardware Room A3<br />
Jeffrey Karg<br />
Boston Innovation, Inc.<br />
101 Rogers Street, #216<br />
Cambridge, Massachusetts 02142<br />
jkarg@bostoninnovation.com<br />
SmartPlate Implementation <strong>and</strong> Return on Investment Examples <strong>for</strong> Compound Management<br />
Assay miniaturization has pushed the limits of compound dispensary logistics. 384 <strong>and</strong> 1536 well screening<br />
requires high quality compounds accurately, reliably, <strong>and</strong> cost-effectively dispensed into a wide range of assay<br />
<strong>for</strong>mats. This time-consuming <strong>and</strong> wasteful step is eliminated with SmartPlate shipping, storing, <strong>and</strong> dispensing<br />
technology. This presentation will highlight how SmartPlate works, as well as providing details on integration with<br />
a variety of liquid h<strong>and</strong>ling equipment. In addition, SmartPlate’s return of investment <strong>for</strong> focused libraries (5–100K<br />
compounds) <strong>and</strong> full size libraries will be explored.<br />
12:15 pm Wednesday, February 4 Emerging Technologies – Hardware Room A3<br />
Hakki Unver<br />
Zymark Corporation<br />
68 Elm Street<br />
Hopkinton, Massachusetts 01748<br />
hounver@hotmail.com<br />
Using Data Collected in Real Time From Liquid Transfer Operations to Audit <strong>and</strong><br />
Enhance Per<strong>for</strong>mance<br />
131<br />
Co-Author(s)<br />
Gregory Wendel, John Howl<strong>and</strong><br />
Zymark Corporation<br />
Mary Jo Wildey<br />
Johnson & Johnson PRD<br />
Channel-by-channel per<strong>for</strong>mance data collected from a liquid transfer device can be utilized to document transfers<br />
<strong>for</strong> regulatory agencies, eliminate false assay results due to transfer failures, provide baselines <strong>for</strong> continuous<br />
improvement, <strong>and</strong> allow <strong>for</strong> immediate corrective action in the transfer method. This presentation describes<br />
the results of experiments with a 96-channel liquid transfer device that measures in real time <strong>and</strong> reports data<br />
about the volume transferred <strong>and</strong> in<strong>for</strong>mation about the quality of the transfer <strong>for</strong> each channel. The experiments<br />
characterized the internal operational data to evolve quality in<strong>for</strong>mation <strong>for</strong> detecting <strong>and</strong> reporting common faults<br />
such as partially clogged tips <strong>and</strong> unexpected air in the channels. Development work explored ways to make the<br />
in<strong>for</strong>mation available to the method developer <strong>for</strong> enabling real time feedback control of the transfer method. Also,<br />
the work explored ways that the device could export the in<strong>for</strong>mation <strong>for</strong> bioin<strong>for</strong>matics data analysis as well as<br />
documentation <strong>for</strong> regulatory agencies.<br />
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