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omation mbers - Society for Laboratory Automation and Screening

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4:00 pm Wednesday, February 4 Genomics – In<strong>for</strong>matics Room A1<br />

Andrei Verner<br />

McGill University <strong>and</strong> Genome Quebec Innovation Centre<br />

740, Doctor Penfield, #7506<br />

Montreal, Quebec, H3A 1A4 Canada<br />

<strong>and</strong>rei.verner@staff.mcgill.ca<br />

Feeding a Multiplat<strong>for</strong>m Genome Center<br />

The McGill University <strong>and</strong> Genome Quebec Innovation Centre consists of 5 plat<strong>for</strong>ms that reflect the main<br />

directions in which genome research technology advanced in the last decade. These are: Genotyping, Sequencing,<br />

Chip, Proteomics, <strong>and</strong> Bioin<strong>for</strong>matics plat<strong>for</strong>ms. All the plat<strong>for</strong>ms function independently, but complement each<br />

other. The advantage of such architecture is that it allows <strong>for</strong> use of different approaches to tackle the same<br />

problem. The principle of mutually complementing approaches is also used within the Genotyping plat<strong>for</strong>m.<br />

Many novel methods of genotyping emerged recently, including those <strong>for</strong> Single Nucleotide Polymorphism (SNP)<br />

genotyping. In our Center SNP-genotyping may be done using 3 different methods. However, none of these SNPgenotyping<br />

techniques have become an obvious method-of-choice, mainly because of a big variety of incoming<br />

parameters. The best strategy depends on multiple factors, including the number of DNA samples, the number of<br />

SNPs to score, the turnaround time, etc. Thus, the old technological conflict between flexibility <strong>and</strong> speed became<br />

the problem of genomics. However, a combination of different techniques provides the recipe <strong>for</strong> success.<br />

4:30 pm Wednesday, February 4 Genomics – In<strong>for</strong>matics Room A1<br />

Roger McIntosh<br />

Silicon Valley Scientific<br />

P.O. Box 66749<br />

Scotts Valley, Cali<strong>for</strong>nia 95067<br />

roger@mcintosh.com<br />

Open Interfacing <strong>for</strong> Lab Aut<strong>omation</strong><br />

This talk describes the design issues <strong>and</strong> development challenges during the three year development <strong>and</strong><br />

deployment of a comprehensive lab aut<strong>omation</strong> software plat<strong>for</strong>m that uses XML <strong>and</strong> web services as its data<br />

interchange mechanism. Alternate data exchange <strong>for</strong>mats, including SOAP, CORBA, <strong>and</strong> DCOM, will be discussed.<br />

Contrasts <strong>and</strong> comparisons of our approach with such alternate data interchange mechanisms, st<strong>and</strong>ardized<br />

data <strong>for</strong>mats, <strong>and</strong> open interfaces will be discussed. This talk should provide significant insight to any group<br />

contemplating design <strong>and</strong> adoption of XML or web service based aut<strong>omation</strong> st<strong>and</strong>ards in the lab, particularly <strong>for</strong><br />

robot <strong>and</strong> instrument aut<strong>omation</strong>. Scheduling <strong>and</strong> control issues will also be discussed.<br />

102

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