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Dames & Moore, 1999 - USDA Forest Service

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effects. The same constituent may exert both kinds of effects. USEPA has developed<br />

toxicitywiteria for most of the constituents detected at the site.<br />

4. Risk Characterization. ,. In risk characterization, exposure and toxicity data were 0<br />

combined to define site-specific cleanup criteria and estimate the nature and magnitude of<br />

potential risks to defined receptor populations. Non-carcinogenic risks to human receptors<br />

were quantified by the haziud quotient (HQ), the ratio of IHS concentration in site media to<br />

the corresponding non-cancer risk-based level multiplied by the acceptable hazard.<br />

Cumulative hazard is expressed as a hazard index (HI). Carcinogenic risks were quantified<br />

by estimating the excess cancer risks, expressed by the ratio of the IHS concentration to the<br />

cancer risk-based levels multiplied by the acceptable cancer risk.<br />

5. Uncertainty Analysis. Like &y other form of modeling, risk assessment relies on a set of<br />

assumptions and estimates, each of which has some element of uncertainty. The<br />

uncertainty analysis accounts for both variability in and lack of knowledge about measured<br />

and estimated parameters, allowing decision makers to better evaluate risk estimates in the<br />

context of the assumptions and &ta used in the assessment.<br />

This Human Health Baseline Risk Assessment was performed in two stages: 1) screening level human<br />

health assessment, and 2) site-specific human health risk assessment. The purpose of the screening level<br />

human health assessment was to produce a comprehensive conceptual site model in order to select<br />

appropriate IHSs. The site-specific HHRA quantified risks and hazards for those pathways considered<br />

significant.<br />

7.1.1.1 Screening Level Human Health Assessment<br />

The methodology for conducting the screening level human health assessment was applied sequentially, as<br />

follows:<br />

Develop a comprehensive, preliminary conceptual site model for the site<br />

Develop criteria for screening data<br />

Conduct data evaluation<br />

Refine the exposure pathways model<br />

Select IHSs<br />

The results of these steps were used to select significant exposure pathways for the site-specific HHRA.<br />

Each step of the screening human health assessment is discussed in detail in Section 7.1.3.<br />

~ : \ ~ ~ u \ ~ ~ ~ ~ ~ l o ~ d c n - z \ r i \ ~ ~ . d o ~ '<br />

17693-0059 I9Uuly 27. <strong>1999</strong>:s: 16 PMDRAFT FINAL RI REPORT

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