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Parathyroid Scintigraphy - European Association of Nuclear Medicine

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1a) is defined by a fixed distance from the axis<br />

<strong>of</strong> rotation to the centre <strong>of</strong> the camera surface<br />

for all angles. Elliptical orbits (Fig. 1b) follow<br />

the body outline more closely.<br />

Figure 1a Figure 1b<br />

Figure 1a circular orbit<br />

Figure 1b elliptical orbit<br />

With a circular orbit, the camera is distant from<br />

the body at some angles, causing a reduction<br />

in spatial resolution in these projections. This<br />

will reduce the resolution <strong>of</strong> the reconstructed<br />

images.<br />

With an elliptical orbit, spatial resolution will be<br />

improved as the camera passes closer to the<br />

body at all angles. Nevertheless, the distance<br />

from the organ to the detector varies more<br />

significantly with an elliptical orbit than with<br />

a circular orbit. This may generate artefacts<br />

simulating small photopenic areas when reconstructing<br />

using filtered back projection.<br />

Programmes that allow the camera to learn<br />

and closely follow the contours <strong>of</strong> the body<br />

1<br />

Chapter 3: Imaging equipment - preparation and use<br />

are available and improve resolution, although<br />

at the expense <strong>of</strong> computing power to modify<br />

the data before reconstruction.<br />

The loss <strong>of</strong> spatial resolution with a circular<br />

orbit has to be <strong>of</strong>fset against the potential artefacts<br />

that may be generated by an elliptical<br />

or contoured orbit.<br />

Filtered back projection image<br />

reconstruction: some considerations<br />

The main goal <strong>of</strong> nuclear medicine parathyroid<br />

imaging procedures is to identify the<br />

site <strong>of</strong> parathyroid hormone production,<br />

usually a single parathyroid adenoma. However,<br />

parathyroid adenomas can be found in<br />

diverse locations: alongside, beside or within<br />

the thyroid, or in anatomical regions distant<br />

from thyroid, such as high or low in the neck<br />

and mediastinum. The diversity <strong>of</strong> these anatomical<br />

locations makes SPECT a useful tool<br />

in parathyroid imaging.<br />

Furthermore, parathyroid adenomas are small<br />

structures with increased uptake <strong>of</strong>ten close<br />

to normal thyroid activity. The choice <strong>of</strong> an<br />

optimum filter when using filtered back projection<br />

for reconstruction is crucial (Pires Jorge<br />

et al. 1998).<br />

A filter in SPECT is a data processing algorithm<br />

that enhances image information, without<br />

significantly altering the components <strong>of</strong> the<br />

input data, creating artefacts or losing information.<br />

It should produce results that lead to<br />

EANM

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