NCI National Clinical Trials Network (NCTN) Program Guidelines

PART 1: Overview of NCTN Program Section IV – Terms/Conditions of Award – Network RT & Imaging
Core Services Centers
Genome Wide Association Studies (GWAS) as well as a biospecimen sharing policy. Network
Radiotherapy & Imaging Core Services Centers are required to follow and support these policies
for the NCTN trials led by the supporting Network Group Operations Centers, if applicable.
5.4.4 Education on the Protection of Human Subjects
NIH policy requires education on the protection of human subject for all investigators submitting
NIH applications for research involving human subjects and individuals designated as key
personnel. This policy is available on the NIH website at:
http://grants.nih.gov/grants/guide/notice-files/NOT-OD-00-039.html.
5.4.5 Other Federal Regulations
The NIH Public Access Policy ensures that the public has access to the published results of NIH
funded research. It requires scientists to submit final peer-reviewed journal manuscripts that
arise from NIH funds to the digital archive PubMed Central upon acceptance for publication. To
help advance science and improve human health, the Policy requires that these papers are
accessible to the public on PubMed Central no later than 12 months after publication. More
information about this policy or the submission process is available on the NIH Public Access
Policy website at: http://publicaccess.nih.gov/.
Information on other federal regulations (and their associated citations/URLs) that may be
applicable to the Network Radiotherapy & Imaging Core Services Centers’ activities is provided in
Part 4: Appendices – Section IV.B.
5.5 Conflict of Interest Policy
The Network Radiotherapy & Imaging Core Services Centers receiving NIH funding from a grant or
cooperative agreement must be in compliance with all of the DHSS regulatory requirements for conflict
of interest as outlined by NIH grants policy available at: http://grants.nih.gov/grants/policy/coi. The
Network Radiotherapy & Imaging Core Services Centers policy should ensure that there is no
reasonable expectation that any investigator of staff member at the Core Centers involved in the
design, conduct, or reporting of research conducted by the Network Group Operations Centers and
their associated Network Group SDMCs will be biased by any conflict of interest (using the definition of
investigator provided in the NIH grants policy). The policy should also be in compliance with the
NCI/DCTD/CTEP’s Conflict of Interest Policy for NCTN Phase 3 Clinical Trials found on the CTEP website
at: http://ctep.cancer.gov/investigatorResources/default.htm#guidelines_policies.
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