NCI National Clinical Trials Network (NCTN) Program Guidelines

PART 1: Overview of NCTN Program Section III – General Management & Network Operating/Funding Principles
III. General Management & Network Operating and Funding Principles
A. General Management
Direct programmatic oversight of the NCTN Program is provided by the NCI Division of Cancer Treatment and
Diagnosis (DCTD) and its programs. The Chief of the Clinical Investigations Branch within the Cancer Therapy
and Evaluation Program (CTEP), DCTD, NCI is the Lead Program Director of the NCTN Program. The Lead
Program Director works with the Co-Program Directors for the key components of the NCTN Program from the
Biometric Research Branch, the Cancer Diagnosis Program, the Cancer Imaging Program, and the Radiation
Research Program as well as other NCI Senior Scientific and Administrative staff from all the branches within
CTEP, other DCTD and NCI programs and offices, and the NCI/DCTD Senior Program Specialist to oversee the
NCTN Program.
NCI/DCTD staff involved with the NCTN Program also work closely with NCI staff from the Division of Cancer
Prevention (DCP), especially DCP program staff for the Community Clinical Oncology Program (CCOP) and the
Minority-Based CCOP (MB-CCOP) Program, to manage the NCTN Program as the CCOPs and MB-CCOPs
participate directly in the clinical trials of the NCTN and the Network Groups of the NCTN also can serve as
Research Bases for the CCOP program. General information on DCTD, DCP, and the programs involved in the
direct programmatic oversight as well as the scientific and administrative activities of the NCTN Program is
available from the NCI public website at the URLs listed below:
NCI Division of Cancer Treatment and Diagnosis (DCTD): http://dctd.cancer.gov/
NCI/DCTD Cancer Therapy Evaluation Program (CTEP): http://ctep.cancer.gov/
NCI/DCTD Biometric Research Program (BRB): http://brb.nci.nih.gov/
NCI/DCTD Cancer Diagnosis Program (CDP): http://dctd.cancer.gov/ProgramPages/cdp/default.htm
NCI/DCTD Cancer Imaging Program (CIP): http://imaging.cancer.gov/
NCI/DCTD Radiation Research Program (RRP): http://rrp.cancer.gov/
NCI Division of Cancer Prevention (DCP): http://prevention.cancer.gov/
NCI/DCP Community Clinical Oncology Program (CCOP) and Minority-Based CCOP (MB-CCOP):
http://prevention.cancer.gov/programs-resources/programs/ccop
External strategic oversight of the NCTN Program is provided by the NCI Clinical Trials and Translational
Research Advisory Committee (CTAC), especially the Strategic Planning Subcommittee of CTAC. Internal
strategic oversight of the NCTN Program is provided by the NCI Clinical and Translational Research Operations
Committee (CTROC). These programs are described in Part 1 – Section I.D.7.5 of these Guidelines.
B. NCTN Leadership Management Committee
The NCTN Leadership Management Committee is composed of key members of NCI/DCTD and NCI/DCP
involved in the direct programmatic oversight of the NCTN Program and the Senior Leaders of the Network
Group Operations Centers, the Network Group Statistics and Data Management Centers, the Network
Radiotherapy and Imaging Core Services Centers, and the Canadian Collaborating Clinical Trials Network
involved in the direct management of clinical trials and support services. This management committee makes
key recommendations regarding the policies, procedures, and conduct of the NCTN Program to the NCI as
described in Part 1 – Section IV.D.4. of these Guidelines). The goal is for the NCI/DCTD and extramural NCTN
senior leadership to work collaboratively in managing the Program.
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