HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...
HYPERTENSION MANAGEMENT AND STROKE PREVENTION ... HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...
8 ALLHAT Pre-Specified Secondary Outcomes (Continued) 4. Combined Cardiovascular Disease [CCVD] (CHD, stroke, coronary revascularizations, heart failure [treated, hospitalized, fatal], angina (treated, hospitalized), peripheral arterial disease (revascularization procedure) 5. Left ventricular hypertrophy by ECG 6. Renal disease a. Slope of reciprocal of creatinine b. End-stage renal disease (dialysis or transplant) 7. HRQL; Major costs of medical care 8. Cancer 9. Gastrointestinal bleeding
9 ALLHAT Inclusion Criteria for Antihypertensive Trial • Age/sex: men and women aged > 55 years • BP eligibility: –Untreated systolic and/or diastolic hypertension (≥ 140/90 mm Hg but ≤ 180/110 mm Hg at two visits) –Treated hypertension • ≤ 160/100 mm Hg on 1-2 antihypertensive drugs at Visit 1 • ≤ 180/110 mm Hg at Visit 2, when medication may have been partially withdrawn –No washout period was required in ALLHAT.
- Page 1 and 2: HYPERTENSION MANAGEMENT AND STROKE
- Page 3 and 4: 3 Hypertension Treatment by Drug Cl
- Page 5 and 6: 5 ALLHAT Antihypertensive Trial Des
- Page 7: 7 ALLHAT Pre-Specified Outcomes All
- Page 11 and 12: 11 ALLHAT ALLHAT Inclusion Criteria
- Page 13 and 14: 13 ALLHAT High-risk hypertensive pa
- Page 15 and 16: 15 ALLHAT Step 2 Agents: Reserpine
- Page 17 and 18: 17 Cumulative Event Rate 0.30 0.25
- Page 19 and 20: 19 ALLHAT 100.0 80.0 60.0 % 40.0 20
- Page 21 and 22: 21 ALLHAT mm Hg BP 150 145 140 135
- Page 23 and 24: 23 Percent ALLHAT 80 60 40 20 0 59
- Page 25 and 26: 25 ALLHAT Cumulative Stroke Rate .1
- Page 27 and 28: 27 ALLHAT Cumulative Mortality Rate
- Page 29 and 30: 29 ALLHAT Total 1.04 (0.99, 1.09) A
- Page 31 and 32: 31 ALLHAT Total 1.38 (1.25, 1.52) A
- Page 33 and 34: 33 ALLHAT AHT: TOTAL CHD AND ALL CA
- Page 35 and 36: 35 ALLHAT Antihypertensive Trial: I
- Page 38 and 39: 38 ALLHAT vs. ANBP-2 • Randomized
- Page 40 and 41: Primary Adjudicated Events - Ramipr
- Page 42 and 43: DOES OBSERVED BP REDUCTION ACCOUNT
- Page 44 and 45: Quartiles ≤124 125-139 140-150 15
- Page 46 and 47: SUBGROUP RESULTS BY OTHER DRUG THER
- Page 48 and 49: 48 Blood Pressure Classification BP
- Page 50 and 51: 50 New Features and Key Messages
- Page 52 and 53: 52 New Features and Key Messages (C
- Page 54 and 55: 54 Algorithm for Treatment of Stage
9<br />
ALLHAT<br />
Inclusion Criteria for<br />
Antihypertensive Trial<br />
• Age/sex: men and women aged > 55 years<br />
• BP eligibility:<br />
–Untreated systolic and/or diastolic hypertension (≥<br />
140/90 mm Hg but ≤ 180/110 mm Hg at two visits)<br />
–Treated hypertension<br />
• ≤ 160/100 mm Hg on 1-2 antihypertensive drugs at<br />
Visit 1<br />
• ≤ 180/110 mm Hg at Visit 2, when medication may<br />
have been partially withdrawn<br />
–No washout period was required in ALLHAT.
Change language