HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...
HYPERTENSION MANAGEMENT AND STROKE PREVENTION ... HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...
6 ALLHAT Secondary Objectives: Pre-specified –Age 65+ –Women Subgroups –African-Americans –Diabetic patients Post-hoc –Baseline CHD
7 ALLHAT Pre-Specified Outcomes All primary and secondary outcomes and their components were pre-specified , i.e., they appeared in the protocol, manual of operations and study forms. Primary Outcome – Coronary Heart Disease (CHD) – fatal CHD or non-fatal MI Secondary Outcomes 1. All-cause death 2. Combined CHD [CCHD] (CHD, coronary revascularizations, or hospitalized angina) 3. Stroke
- Page 1 and 2: HYPERTENSION MANAGEMENT AND STROKE
- Page 3 and 4: 3 Hypertension Treatment by Drug Cl
- Page 5: 5 ALLHAT Antihypertensive Trial Des
- Page 9 and 10: 9 ALLHAT Inclusion Criteria for Ant
- Page 11 and 12: 11 ALLHAT ALLHAT Inclusion Criteria
- Page 13 and 14: 13 ALLHAT High-risk hypertensive pa
- Page 15 and 16: 15 ALLHAT Step 2 Agents: Reserpine
- Page 17 and 18: 17 Cumulative Event Rate 0.30 0.25
- Page 19 and 20: 19 ALLHAT 100.0 80.0 60.0 % 40.0 20
- Page 21 and 22: 21 ALLHAT mm Hg BP 150 145 140 135
- Page 23 and 24: 23 Percent ALLHAT 80 60 40 20 0 59
- Page 25 and 26: 25 ALLHAT Cumulative Stroke Rate .1
- Page 27 and 28: 27 ALLHAT Cumulative Mortality Rate
- Page 29 and 30: 29 ALLHAT Total 1.04 (0.99, 1.09) A
- Page 31 and 32: 31 ALLHAT Total 1.38 (1.25, 1.52) A
- Page 33 and 34: 33 ALLHAT AHT: TOTAL CHD AND ALL CA
- Page 35 and 36: 35 ALLHAT Antihypertensive Trial: I
- Page 38 and 39: 38 ALLHAT vs. ANBP-2 • Randomized
- Page 40 and 41: Primary Adjudicated Events - Ramipr
- Page 42 and 43: DOES OBSERVED BP REDUCTION ACCOUNT
- Page 44 and 45: Quartiles ≤124 125-139 140-150 15
- Page 46 and 47: SUBGROUP RESULTS BY OTHER DRUG THER
- Page 48 and 49: 48 Blood Pressure Classification BP
- Page 50 and 51: 50 New Features and Key Messages
- Page 52 and 53: 52 New Features and Key Messages (C
- Page 54 and 55: 54 Algorithm for Treatment of Stage
6<br />
ALLHAT<br />
Secondary Objectives:<br />
Pre-specified<br />
–Age 65+<br />
–Women<br />
Subgroups<br />
–African-Americans<br />
–Diabetic patients<br />
Post-hoc<br />
–Baseline CHD