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HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...

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Primary Adjudicated Events<br />

- Ramipril vs Placebo 1/2<br />

Ramipril<br />

(%)<br />

No. Rand. 4645 4652<br />

1°Outcome<br />

Placebo<br />

(%)<br />

RR 95% CI p<br />

MI,Stroke,CVDth 14.1 17.7 0.78 0.70-0.86 0.000002<br />

CV Death* 6.1 8.1 0.75 0.64-0.87 0.0002<br />

MI* 9.9 12.2 0.80 0.71-0.91 0.0005<br />

Stroke* 3.4 4.9 0.69 0.56-0.84 0.0003<br />

Non-CV Death 4.3 4.1 1.03 0.84-1.25 0.78<br />

Mortality 10.4 12.2 0.84 0.75-0.95 0.0058<br />

*not mutually exclusive

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