HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...
HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...
HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...
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36<br />
SECOND AUSTRALIAN NATIONAL<br />
BLOOD PRESSURE STUDY (ANBP-2)<br />
• Enalapril/ACEI vs. HCTZ, n = 6,083<br />
• Randomized, open-label (blinded endpoint review)<br />
• All CV events or death from any cause<br />
– HR = 0.89 (0.79-1.00), p=0.05 (adjusted)<br />
• First events<br />
– CVD: HR = 0.88 (0.77-1.01), p = 0.07<br />
– CHD: HR = 0.86 (0.70-1.06), p = 0.16<br />
– Stroke: HR = 1.02 (0.78-1.33), p = 0.91<br />
– HF: HR = 0.85 (0.62-1.18), p = 0.33<br />
NEJM 2003;348:583-92
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