HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...

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30 ALLHAT Cumulative CHF Rate .15 .12 .09 .06 .03 0 Cumulative Event Rates for Heart Failure by ALLHAT Treatment Group A/C L/C HR (95% CI) 1.38 (1.25-1.52) 1.19 (1.07-1.31) Chlorthalidone Amlodipine Lisinopril p value
31 ALLHAT Total 1.38 (1.25, 1.52) Age < 65 1.51 (1.25, 1.82) Age >= 65 1.33 (1.18, 1.49) Men 1.41 (1.24, 1.61) Women 1.33 (1.14, 1.55) Black 1.47 (1.24, 1.74) Non-Black 1.33 (1.18, 1.51) Diabetic 1.42 (1.23, 1.64) Non-Diabetic 1.33 (1.16, 1.52) 0.50 1 2 Amlodipine Better Chlorthalidone Better Heart Failure – Subgroup Comparisons – RR (95% CI) Total 1.20 (1.09, 1.34) Age < 65 1.23 (1.01, 1.50) Age >= 65 1.20 (1.06, 1.35) Men 1.19 (1.03, 1.36) Women 1.23 (1.05, 1.43) Black 1.32 (1.11, 1.58) Non-Black 1.15 (1.01, 1.30) Diabetic 1.22 (1.05, 1.42) Non-Diabetic 1.20 (1.04, 1.38) 0.50 1 2 Lisinopril Better Chlorthalidone Better
Page 1 and 2: HYPERTENSION MANAGEMENT AND STROKE
Page 3 and 4: 3 Hypertension Treatment by Drug Cl
Page 5 and 6: 5 ALLHAT Antihypertensive Trial Des
Page 7 and 8: 7 ALLHAT Pre-Specified Outcomes All
Page 9 and 10: 9 ALLHAT Inclusion Criteria for Ant
Page 11 and 12: 11 ALLHAT ALLHAT Inclusion Criteria
Page 13 and 14: 13 ALLHAT High-risk hypertensive pa
Page 15 and 16: 15 ALLHAT Step 2 Agents: Reserpine
Page 17 and 18: 17 Cumulative Event Rate 0.30 0.25
Page 19 and 20: 19 ALLHAT 100.0 80.0 60.0 % 40.0 20
Page 21 and 22: 21 ALLHAT mm Hg BP 150 145 140 135
Page 23 and 24: 23 Percent ALLHAT 80 60 40 20 0 59
Page 25 and 26: 25 ALLHAT Cumulative Stroke Rate .1
Page 27 and 28: 27 ALLHAT Cumulative Mortality Rate
Page 29: 29 ALLHAT Total 1.04 (0.99, 1.09) A
Page 33 and 34: 33 ALLHAT AHT: TOTAL CHD AND ALL CA
Page 35 and 36: 35 ALLHAT Antihypertensive Trial: I
Page 38 and 39: 38 ALLHAT vs. ANBP-2 • Randomized
Page 40 and 41: Primary Adjudicated Events - Ramipr
Page 42 and 43: DOES OBSERVED BP REDUCTION ACCOUNT
Page 44 and 45: Quartiles ≤124 125-139 140-150 15
Page 46 and 47: SUBGROUP RESULTS BY OTHER DRUG THER
Page 48 and 49: 48 Blood Pressure Classification BP
Page 50 and 51: 50 New Features and Key Messages
Page 52 and 53: 52 New Features and Key Messages (C
Page 54 and 55: 54 Algorithm for Treatment of Stage

HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...

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