HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...
HYPERTENSION MANAGEMENT AND STROKE PREVENTION ... HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...
28 ALLHAT Cumulative Combined CVD Event Rate .5 .4 .3 .2 .1 0 A/C L/C Cumulative Event Rates for Combined CVD by ALLHAT Treatment Group RR (95% CI) 1.04 (0.99-1.09) 1.10 (1.05-1.16) Chlorthalidone Amlodipine Lisinopril p value 0.12
29 ALLHAT Total 1.04 (0.99, 1.09) Age < 65 1.03 (0.94, 1.12) Age >= 65 1.05 (0.99, 1.12) Men 1.04 (0.98, 1.11) Women 1.04 (0.96, 1.13) Black 1.06 (0.96, 1.16) Non-Black 1.04 (0.97, 1.10) Diabetic 1.06 (0.98, 1.15) Non-Diabetic 1.02 (0.96, 1.09) 0.50 1 2 Combined CVD – Subgroup Comparisons – RR (95% CI) Amlodipine Better Chlorthalidone Better Total 1.10 (1.05, 1.16) Age < 65 1.05 (0.97, 1.15) Age >= 65 1.13 (1.06, 1.20) Men 1.08 (1.02, 1.15) Women 1.12 (1.03, 1.21) Black 1.19 (1.09, 1.30) Non-Black 1.06 (1.00, 1.13) Diabetic 1.08 (1.00, 1.17) Non-Diabetic 1.12 (1.05, 1.19) 0.50 1 2 Lisinopril Better Chlorthalidone Better P = .04 for interaction
- Page 1 and 2: HYPERTENSION MANAGEMENT AND STROKE
- Page 3 and 4: 3 Hypertension Treatment by Drug Cl
- Page 5 and 6: 5 ALLHAT Antihypertensive Trial Des
- Page 7 and 8: 7 ALLHAT Pre-Specified Outcomes All
- Page 9 and 10: 9 ALLHAT Inclusion Criteria for Ant
- Page 11 and 12: 11 ALLHAT ALLHAT Inclusion Criteria
- Page 13 and 14: 13 ALLHAT High-risk hypertensive pa
- Page 15 and 16: 15 ALLHAT Step 2 Agents: Reserpine
- Page 17 and 18: 17 Cumulative Event Rate 0.30 0.25
- Page 19 and 20: 19 ALLHAT 100.0 80.0 60.0 % 40.0 20
- Page 21 and 22: 21 ALLHAT mm Hg BP 150 145 140 135
- Page 23 and 24: 23 Percent ALLHAT 80 60 40 20 0 59
- Page 25 and 26: 25 ALLHAT Cumulative Stroke Rate .1
- Page 27: 27 ALLHAT Cumulative Mortality Rate
- Page 31 and 32: 31 ALLHAT Total 1.38 (1.25, 1.52) A
- Page 33 and 34: 33 ALLHAT AHT: TOTAL CHD AND ALL CA
- Page 35 and 36: 35 ALLHAT Antihypertensive Trial: I
- Page 38 and 39: 38 ALLHAT vs. ANBP-2 • Randomized
- Page 40 and 41: Primary Adjudicated Events - Ramipr
- Page 42 and 43: DOES OBSERVED BP REDUCTION ACCOUNT
- Page 44 and 45: Quartiles ≤124 125-139 140-150 15
- Page 46 and 47: SUBGROUP RESULTS BY OTHER DRUG THER
- Page 48 and 49: 48 Blood Pressure Classification BP
- Page 50 and 51: 50 New Features and Key Messages
- Page 52 and 53: 52 New Features and Key Messages (C
- Page 54 and 55: 54 Algorithm for Treatment of Stage
28<br />
ALLHAT<br />
Cumulative Combined CVD Event Rate<br />
.5<br />
.4<br />
.3<br />
.2<br />
.1<br />
0<br />
A/C<br />
L/C<br />
Cumulative Event Rates for Combined<br />
CVD by ALLHAT Treatment Group<br />
RR (95% CI)<br />
1.04 (0.99-1.09)<br />
1.10 (1.05-1.16)<br />
Chlorthalidone<br />
Amlodipine<br />
Lisinopril<br />
p value<br />
0.12<br />
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