HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...

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10 ALLHAT ALLHAT Inclusion Criteria: Risk Factors At least one of the following: • Myocardial infarction or stroke: at least 6 months old, or age-indeterminate • History of revascularization procedure • Major ST segment depression or T-wave inversion • Other documented ASCVD
11 ALLHAT ALLHAT Inclusion Criteria: Risk Factors At least one of the following (cont.) • Type 2 diabetes mellitus • HDL cholesterol < 35 mg/dL on any 2 or more determinations in past 5 years • Left ventricular hypertrophy (past 2 years) – ECG, or echo (septum + posterior wall thickness ≥ 25 mm) • Current cigarette smoking
Page 1 and 2: HYPERTENSION MANAGEMENT AND STROKE
Page 3 and 4: 3 Hypertension Treatment by Drug Cl
Page 5 and 6: 5 ALLHAT Antihypertensive Trial Des
Page 7 and 8: 7 ALLHAT Pre-Specified Outcomes All
Page 9: 9 ALLHAT Inclusion Criteria for Ant
Page 13 and 14: 13 ALLHAT High-risk hypertensive pa
Page 15 and 16: 15 ALLHAT Step 2 Agents: Reserpine
Page 17 and 18: 17 Cumulative Event Rate 0.30 0.25
Page 19 and 20: 19 ALLHAT 100.0 80.0 60.0 % 40.0 20
Page 21 and 22: 21 ALLHAT mm Hg BP 150 145 140 135
Page 23 and 24: 23 Percent ALLHAT 80 60 40 20 0 59
Page 25 and 26: 25 ALLHAT Cumulative Stroke Rate .1
Page 27 and 28: 27 ALLHAT Cumulative Mortality Rate
Page 29 and 30: 29 ALLHAT Total 1.04 (0.99, 1.09) A
Page 31 and 32: 31 ALLHAT Total 1.38 (1.25, 1.52) A
Page 33 and 34: 33 ALLHAT AHT: TOTAL CHD AND ALL CA
Page 35 and 36: 35 ALLHAT Antihypertensive Trial: I
Page 38 and 39: 38 ALLHAT vs. ANBP-2 • Randomized
Page 40 and 41: Primary Adjudicated Events - Ramipr
Page 42 and 43: DOES OBSERVED BP REDUCTION ACCOUNT
Page 44 and 45: Quartiles ≤124 125-139 140-150 15
Page 46 and 47: SUBGROUP RESULTS BY OTHER DRUG THER
Page 48 and 49: 48 Blood Pressure Classification BP
Page 50 and 51: 50 New Features and Key Messages
Page 52 and 53: 52 New Features and Key Messages (C
Page 54 and 55: 54 Algorithm for Treatment of Stage

HYPERTENSION MANAGEMENT AND STROKE PREVENTION ...

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