5th EuropEan MolEcular IMagIng MEEtIng - ESMI

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5th EuropEan MolEcular IMagIng MEEtIng – EMIM2010 • ESMI Plenary Lecture 1: Violaine Sée (Liverpool, UK) Transcription factors dynamics: from discrete pulses to oscillatory pattern to control gene expression Chairs: Clemens W.G.M. Löwik (Leiden, The Netherlands) , Leszek Krolicki (Warsaw, Poland) • Parallel Session 1: Cancer I – together with ESR Chairs: Markus Schwaiger (Munich, Germany), Peter Brader (Vienna, Austria) • Parallel Session 2: Neuroscience I Chairs: Annemie van der Linden (Antwerp, Belgium), David Wyper (Glasgow, UK), Hervé Boutin (Manchester, UK) • Parallel Session 3: Technology Chairs: Jorge Ripoll (Heraklion, Greece) , Bernd Pichler (Tuebingen, Germany) • Parallel Session 4: Probes I – together with COST Chairs: Eva Jakab-Tóth (Orléans, France) , Silvio Aime (Torino, Italy) • ESMI Plenary Lecture 2: Francesca Odoardi (Göttingen, Germany) Immune surveillance and autoimmunity: how encephalitogenic T cells enter their target organ Chairs: Renata Mikolajczak (Warsaw, Poland), Chrit Moonen (Bordeaux, France) • Plenary Session on Excellent and Late Breaking Abstracts Chairs: Renata Mikolajczak (Warsaw, Poland), Chrit Moonen (Bordeaux, France) Day 1 - Thursday May 27, 2010 EuropEan SocIEty for MolEcular IMagIng – ESMI day1 Day 1 - Thursday May 27, 2010
24 WarSaW, poland May 26 – 29, 2010 Violaine Sée is a BBSRC David Phillips Research Fellow at the University of Liverpool. She graduated in Chemistry and Molecular and Cellular Biology at the University Louis Pasteur in Strasbourg (France). After a Master in Pharmacology, in 2001 she obtained her PhD in Pharmacology and Neurobiology at the University Louis Pasteur. She was then assistant lecturer and subsequently moved to the University of Liverpool as a Post-doctoral Research Fellow. In 2005, she obtained a prestigious David Phillips Fellowship, to develop her work on intracellular signalling dynamics. She is focusing on the imaging of single living cells in order to understand regulation of gene transcription and cell fate. She has recently been interested in using new techniques for single molecule imaging in live cells based on the use of gold nanoparticles. Selected References • Nelson, D. E., Ihekwaba, A. E., Elliott, M., Johnson, J. R., Gibney, C. A., Foreman, B. E., Nelson, G., See, V., Horton, C. A., Spiller, D. G., Edwards, S. W., McDowell, H. P., Unitt, J. F., Sullivan, E., Grimley, R., Benson, N., Broomhead, D., Kell, D. B., and White, M. R. (2004) Oscillations in NF-kappaB signaling control the dynamics of gene expression. Science 306, 704-708 • See, V., Rajala, N. K., Spiller, D. G., and White, M. R. (2004) Calcium-dependent regulation of the cell cycle via a novel MAPK--NF-kappaB pathway in Swiss 3T3 cells. The Journal of cell biology 166, 661-672 • Nelson, D. E., See, V., Nelson, G., and White, M. R. (2004) Oscillations in transcription factor dynamics: a new way to control gene expression. Biochemical Society transactions 32, 1090-1092 • Ashall, L., Horton, C. A., Nelson, D. E., Paszek, P., Harper, C. V., Sillitoe, K., Ryan, S., Spiller, D. G., Unitt, J. F., Broomhead, D. S., Kell, D. B., Rand, D. A., See, V., and White, M. R. (2009) Pulsatile stimulation determines timing and specificity of NFkappaB-dependent transcription. Science 324, 242-246 • See, V., Free, P., Cesbron, Y., Nativo, P., Shaheen, U., Rigden, D. J., Spiller, D. G., Fernig, D. G., White, M. R., Prior, I. A., Brust, M., Lounis, B., and Levy, R. (2009) Cathepsin L digestion of nanobioconjugates upon endocytosis. ACS nano 3, 2461- 2468 • Meley, D., Spiller, D.G., White, M.R., McDowell, H., Pizer, B.L., and See, V. (2010) p53-mediated delayed NF-kB activity enhances etoposide-induced cell death in medulloblastoma. Cell Death and Disease 1, In press imaging life Violaine Sée
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ANIMASCOPE High TECHNOLOGY for High
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5th EuropEan MolEcular IMagIng MEEtIng - ESMI

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