2 - TI Pharma

89. Seckl jR, Morton NM, Chapman KE, Walker BR. Glucocorticoids and 11beta-hydroxysteroid
dehydrogenase in adipose tissue. Recent Prog Horm Res. 2004;59:359-93.
90. Kahn SE. The relative contributions of insulin resistance and beta-cell dysfunction to the
pathophysiology of Type 2 diabetes. Diabetologia. 2003;46(1):3-19.
91. Weyer C, Bogardus C, Mott DM, Pratley RE. The natural history of insulin secretory dysfunction and
insulin resistance in the pathogenesis of type 2 diabetes mellitus. j Clin Invest. 1999;104(6):787-94.
92. Barseghian G, Levine R. Effect of corticosterone on insulin and glucagon secretion by the isolated
perfused rat pancreas. Endocrinology. 1980;106(2):547-52.
93. Billaudel B, Mathias PC, Sutter BC, Malaisse WJ. Inhibition by corticosterone of calcium inflow and
insulin release in rat pancreatic islets. j Endocrinol. 1984;100(2):227-33.
94. Brunstedt j, Nielsen jH. Direct long-term effect of hydrocortisone on insulin and glucagon release
from mouse pancreatic islets in tissue culture. Acta Endocrinol (Copenh). 1981;96(4):498-504.
95. Gremlich S, Roduit R, Thorens B. Dexamethasone induces posttranslational degradation of GLUT2
and inhibition of insulin secretion in isolated pancreatic beta cells. Comparison with the effects of
fatty acids. j Biol Chem. 1997;272(6):3216-22.
96. jeong IK, Oh SH, Kim Bj, Chung jH, Min YK, Lee MS, Lee MK, Kim KW. The effects of dexamethasone
on insulin release and biosynthesis are dependent on the dose and duration of treatment. Diabetes
Res Clin Pract. 2001;51(3):163-71.
97. Pierluissi j, Navas FO, Ashcroft Sj. Effect of adrenal steroids on insulin release from cultured rat islets
of Langerhans. Diabetologia. 1986;29(2):119-21.
98. Ullrich S, Berchtold S, Ranta F, Seebohm G, Henke G, Lupescu A, Mack AF, Chao CM, Su j, Nitschke
R, Alexander D, Friedrich B, Wulff P, Kuld D, Lang F. Serum- and glucocorticoid-inducible kinase 1
(SGK1) mediates glucocorticoid-induced inhibition of insulin secretion. Diabetes. 2005;54(4):1090-
9.
99. Zawalich WS, Tesz Gj, Yamazaki H, Zawalich KC, Philbrick W. Dexamethasone suppresses
phospholipase C activation and insulin secretion from isolated rat islets. Metabolism. 2006;55(1):35-
42.
100. Nesher R, Anteby E, Yedovizky M, Warwar N, Kaiser N, Cerasi E. Beta-cell protein kinases and the
dynamics of the insulin response to glucose. Diabetes. 2002;51 Suppl 1:S68-73.
101. Ogawa A, johnson jH, Ohneda M, McAllister CT, Inman L, Alam T, Unger RH. Roles of insulin resistance
and beta-cell dysfunction in dexamethasone-induced diabetes. j Clin Invest. 1992;90(2):497-504.
102. Borboni P, Porzio O, Magnaterra R, Fusco A, Sesti G, Lauro R, Marlier LN. Quantitative analysis of
pancreatic glucokinase gene expression in cultured beta cells by competitive polymerase chain
reaction. Mol Cell Endocrinol. 1996;117(2):175-81.
103. Khan A, Ostenson CG, Berggren PO, Efendic S. Glucocorticoid increases glucose cycling and inhibits
insulin release in pancreatic islets of ob/ob mice. Am j Physiol. 1992;263(4 Pt 1):E663-6.
47
2
Chapter 2