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Chapter 2 Glucocorticoids: metabolic side effects<br />

46. Schneiter P, Tappy L. Kinetics of dexamethasone-induced alterations of glucose metabolism in<br />

healthy humans. Am j Physiol. 1998;275(5 Pt 1):E806-13.<br />

47. Shamoon H, Soman V, Sherwin RS. The influence of acute physiological increments of cortisol on<br />

fuel metabolism and insulin binding to monocytes in normal humans. j Clin Endocrinol Metab.<br />

1980;50(3):495-501.<br />

48. Wajngot A, Khan A, Giacca A, Vranic M, Efendic S. Dexamethasone increases glucose cycling, but not<br />

glucose production, in healthy subjects. Am j Physiol. 1990;259(5 Pt 1):E626-32.<br />

49. jin jY, Dubois DC, Almon RR, jusko Wj. Receptor/gene-mediated pharmacodynamic effects of<br />

methylprednisolone on phosphoenolpyruvate carboxykinase regulation in rat liver. j <strong>Pharma</strong>col Exp<br />

Ther. 2004;309(1):328-39.<br />

50. Sasaki K, Cripe TP, Koch SR, Andreone TL, Petersen DD, Beale EG et al. Multihormonal regulation of<br />

phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin. j Biol Chem.<br />

1984;259(24):15242-51.<br />

51. Vander Kooi BT, Onuma H, Oeser JK, Svitek CA, Allen SR, Vander Kooi CW, Chazin WJ, O’Brien RM.<br />

The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative<br />

glucocorticoid response elements. Mol Endocrinol. 2005;19(12):3001-22.<br />

52. Zimmerman T, Horber F, Rodriguez N, Schwenk WF, Haymond MW. Contribution of insulin resistance<br />

44<br />

to catabolic effect of prednisone on leucine metabolism in humans. Diabetes. 1989;38(10):1238-44.<br />

53. Kraus-Friedmann N. Hormonal regulation of hepatic gluconeogenesis. Physiol Rev. 1984;64(1):170-<br />

259.<br />

54. Whorwood CB, Donovan Sj, Flanagan D, Phillips DI, Byrne CD. Increased glucocorticoid receptor<br />

expression in human skeletal muscle cells may contribute to the pathogenesis of the metabolic<br />

syndrome. Diabetes. 2002;51(4):1066-75.<br />

55. Chevalier S, Burgess SC, Malloy CR, Gougeon R, Marliss EB, Morais jA. The greater contribution<br />

of gluconeogenesis to glucose production in obesity is related to increased whole-body protein<br />

catabolism. Diabetes. 2006;55(3):675-81.<br />

56. Dirlewanger M, Schneiter PH, Paquot N, jequier E, Rey V, Tappy L. Effects of glucocorticoids on<br />

hepatic sensitivity to insulin and glucagon in man. Clin Nutr. 2000;19(1):29-34.<br />

57. Bernal-Mizrachi C, Weng S, Feng C, Finck BN, Knutsen RH, Leone TC, Coleman T, Mecham RP, Kelly DP,<br />

Semenkovich CF. Dexamethasone induction of hypertension and diabetes is PPAR-alpha dependent<br />

in LDL receptor-null mice. Nat Med 2003;9(8):1069-75.<br />

58. Bernal-Mizrachi C, Xiaozhong L, Yin L, Knutsen RH, Howard Mj, Arends jj, Desantis P, Colemant<br />

T, Semenkovich CF. An afferent vagal nerve pathway links hepatic PPARalpha activation to<br />

glucocorticoid-induced insulin resistance and hypertension. Cell Metab. 2007;5(2):91-102.<br />

59. Van Raalte DH, Li M, Pritchard PH, Wasan KM. Peroxisome proliferator-activated receptor (PPAR)alpha:<br />

a pharmacological target with a promising future. Pharm Res. 2004;21(9):1531-8.

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