2 - TI Pharma

SUPPLEMENTAL FIGURES
Supplemental Figure 1. Overview of the meal challenge test (A) and the combined hyperinsulinemiceuglycemic
and hyperglycemic clamp procedure (B). Note that exenatide was infused during the
hyperglycemic clamp, but not during the euglycemic clamp. Abbreviations: EXE: exenatide; PRED:
prednisolone.
Supplemental Figure 2. Exenatide plasma levels equaled 65 ± 4 pg/mL between T = 0 and T = 240 of the
meal challenge (A) and 80 ± 4 pg/mL between T = -30 and T = 110 of the hyperglycemic clamp (B). Mean
± SEM are depicted.
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Chapter 7