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2 - TI Pharma

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Figure 3. Postprandial responses at baseline and at 14 day of intervention. Panel A: Glucose concentrations.<br />

Panel B: Insulin concentrations. Panel C: C-peptide concentrations. Panel D: Glucagon-like peptide (GLP)-<br />

1 concentrations. Panel E: Glucose-dependent insulinotropic polypeptide (GIP) concentrations. Panel F:<br />

Glucagon concentrations. Straight line with black squares denotes pre-treatment. Dotted line with open<br />

circles represents on-treatment. Box-and-Whisker plots with absolute change in area under the curve<br />

(AUC) from baseline are shown. Between-group changes from baseline were tested by Kruskal-Wallis test<br />

with trend analysis (indicated by top line). Posthoc tests were done by Mann-Whitney U with Bonferroni<br />

correction for multiple testing (indicated by line with brackets). ***P

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