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Scientific Program Committee

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Wednesday<br />

February 6 Sessions<br />

Session 40 CROI 2008<br />

c Wednesday, 2-3 pm; Room 311<br />

CME<br />

Session 40–Poster Discussion<br />

(see Session 49 on Tuesday for corresponding Poster Abstracts)<br />

New Insights into APOBEC Proteins<br />

Discussants:<br />

Francois Clavel, Hosp Bichat, Paris, France<br />

Welkin Johnson, New England Primate Res Ctr, Harvard Med Sch, Southborough,<br />

MA, US<br />

229 Deamination in 3D: Intra- and Intersegmental Transfer of<br />

APOBEC3G Cytidine Deaminase<br />

Roni Nowarski*, M Kotler, and E Britan<br />

Hebrew Univ, Hadassah Med Sch, Jerusalem, Israel<br />

230 APOBEC3G’s Cytoplasmic Localization Is Actively<br />

Regulated but Not Required for HIV-1 Restriction<br />

Mark Stenglein* and R Harris<br />

Univ of Minnesota, Minneapolis, US<br />

231 Enzymatically Active APOBEC3G Is Required for Efficient<br />

Inhibition of HIV-1<br />

E Miyagi, S Opi, H Takeuchi, M Khan, R Goila-Gaur, S Kao, and<br />

Klaus Strebel*<br />

NIH, Bethesda, MD, US<br />

232 Distinct Packaging Mechanisms of Human Cytidine<br />

Deaminase APOBEC3 Proteins into HIV-1 Virions<br />

Lindi Tan*, T Wang, and X Yu<br />

Johns Hopkins Univ, Baltimore, MD, US<br />

233 Effect of Impaired Processivity of HIV-1 Reverse<br />

Transcriptase on the G-to-A Mutation Rate Induced by<br />

APOBEC-3G/-3F<br />

Stefanie Knoepfel*, P Rauch, N Salisch, K Allers, P Huelsmann, and<br />

K Metzner<br />

Univ of Erlangen-Nuremberg, Germany<br />

234 Protein Kinase A-mediated Phophorylation of APOBEC3G<br />

Antagonizes Its Degradation by Vif<br />

Kotaro Shirakawa*, A Takaori-Kondo, T Izumi, K Io, M Matsui, and<br />

T Uchiyama<br />

Kyoto Univ, Japan<br />

22 15th Conference on Retroviruses and Opportunistic Infections<br />

c Wednesday, 2-3 pm; Room 312<br />

CME<br />

Session 41–Poster Discussion<br />

(see Session 84 on Monday for corresponding Poster Abstracts)<br />

Molecular Epidemiology: The Americas<br />

Discussants:<br />

Beatrice Hahn, Univ of Alabama at Birmingham, US<br />

Andrew Leigh Brown, Univ of Edinburgh, Scotland<br />

505 HIV-1 Transmission Dynamics in Quebec in the HAART Era<br />

Bluma Brenner* 1 , M Roger 2 , D Moisi 1 , J Cox 3 , JP Routy 1 , M Wainberg 1 , and<br />

Quebec PHI Study Group<br />

1 McGill AIDS Ctr, Jewish Gen Hosp, Montreal, Canada; 2 Ctr Hosp Univ<br />

Montreal, Canada; and 3 Quebec Agency of Publ Hlth and Social Svcs,<br />

Canada<br />

506 Tracking Molecular Epidemiology of HIV-1 in Mexico:<br />

Emergence of BG Intersubtype Recombinant<br />

Eduardo Vazquez-Valls* 1 , M Escoto-Delgadillo 1 , R Carabez-Hernandez 2 ,<br />

and B Torres-Mendoza 2<br />

1 UMAE Specialties Hosp, Western Biomed Res Ctr, Mexican Inst of Social<br />

Security, Guadalajara and 2 Univ Hlth Sci Ctr, Univ of Guadalajara,<br />

Mexico<br />

507 Evolutionary Dynamics of HIV-1 BF and CB Recombinants<br />

in South America<br />

Elcio Leal* 1 , L Martins 2 , M Janini 1 , and R Diaz 1<br />

1 Federal Univ of Sao Paulo, Brazil and 2 Grad Sch of Agriculture and Life<br />

Sci, Univ of Tokyo, Japan<br />

508 A Foothold for Subtype C in the Americas: Risk Factors<br />

Associated with Subtype C and Non-Subtype C HIV<br />

Infection among HIV Testing Clients in South Brazil<br />

Oliver Bacon* 1 , R da Silva de Souza 2 , K Page Shafer 1 , R Diaz 3 , V Debastiani 4 ,<br />

G Preussler 5 , M Leticia Ikeda 6 , N Barcellos 7 , W Steward 1 , and C Pilcher 1<br />

1 Univ of California, San Francisco, US; 2 Univ de Caxias do Sul, Rio<br />

Grande, Brazil; 3 Paulista Sch of Med, Federal Univ of Sao Paulo, Brazil;<br />

4 Ambulatorio de DST/AIDS, Caxias do Sul, Rio Grande do Sul, Brazil;<br />

5 Svc de Assistencia Especializado, Ctr de Saude Vila dos Comercarios,<br />

Rio Grande do Sul, Brazil; 6 Svc Especializado de DST/AIDS Herbert de<br />

Souza, Rio Grande do Sul, Brazil; and 7 Hosp Sanatorio Partenon, Rio<br />

Grande do Sul, Brazil<br />

509 Timing the Introduction of HIV-1 Subtype C in Brazil<br />

Gonzalo Bello*, R Lorete, M Guimaraes, C Bittencourt Passaes, and<br />

M Morgado<br />

Oswaldo Cruz Inst, Fiocruz, Rio de Janeiro, Brazil

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