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Joint International Conference on Long-term Experiments ...

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• The in<strong>term</strong>ediary form appears between 25 – 45%, and dyspnoea, tachycardia, cardiac<br />

breath, headaches are added to the symptoms characteristic to the superficial form<br />

• The severe form appears over 50%, c<strong>on</strong>vulsi<strong>on</strong>s, arhytmia, coma and even death (blue<br />

death due to asphyxia) being added to the previously menti<strong>on</strong>ed symptoms<br />

characteristic for superficial and in<strong>term</strong>ediary forms of the disease<br />

The disease is present almost exclusively in little children, from the first year of their life,<br />

who are fed artificially (Ciofu E., Ciofu C, 1999, Apllet<strong>on</strong> & Lange, 1993), due to the<br />

following special physiological characteristics of the sucklings:<br />

• Gastric acidity is lower in the first m<strong>on</strong>ths of life;<br />

• 80% of the suckling’s Hb is of fetal type, being more unstable and easier to be oxidized<br />

in comparis<strong>on</strong> with the adult’s Hb.;<br />

• Water quantity (hence of nitrates) ingested by the baby, with respect to the blood<br />

volume, is about 12 times higher than in the case of an adult;<br />

• Some enzymatic deficiencies (deficit of glucoso-6-phosphate-dehydrogenase) favour<br />

the appearance of the disease;<br />

• A high frequency disease rate in athrepsic suckling, with gastro-intestinal perturbati<strong>on</strong>s<br />

and infecti<strong>on</strong>s.<br />

MATERIALS AND METHODS<br />

The study was made <strong>on</strong> 17 sucklings from some rural places of Bihor county, hospitalized<br />

in 2006. The methodology that was used during the experiment was imposed by Ministry of<br />

Family and Health, by studying t€he medical records sent by the health units with beds to<br />

the Public Health Directorate of Bihor County.<br />

The data collected from these medical records are presented in the following tables:<br />

Table 1. Data collected from the patients’ medical records<br />

Case No. Sex Age till the<br />

debut<br />

(m<strong>on</strong>ths)<br />

Alimentati<strong>on</strong> Associati<strong>on</strong><br />

with BDA<br />

Clinical<br />

form<br />

1 male 1-2 natural no Sever<br />

2 female 0-1 mixed no Medium<br />

3 female 0-1 Natural no Sever<br />

4 male 0-1 Artificial no Sever<br />

5 female 7-8 Artificial no Medium<br />

6 female 2-3 Natural no Sever<br />

7 female 0-1 Mixed yes Sever<br />

8 male 1-2 Artificial yes Sever<br />

9 female 0-1 natural no Medium<br />

10 male 2-3 artificial no Medium<br />

581

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