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Joint International Conference on Long-term Experiments ...

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CLINICAL AND EPIDEMIOLOGICAL ASPECTS OF<br />

HEPATIC HYDATID CYST<br />

Mirela Indrieş, Viorica Coldea, Cristian Brisc, Ildiko Lenard, S<strong>on</strong>ia Drăghici,<br />

Andrei Csep, Daciana Sabău, Nicoleta Negruţ<br />

University of Oradea, Faculty of Medicineand Pharmacy Oradea<br />

ABSTRACT<br />

Human echinococcosis is a zo<strong>on</strong>otic infecti<strong>on</strong> caused by the tapeworm of the genus<br />

Echinococcus. Human disease is a „dead end” which interrupts the life cycle of the<br />

parasite. Hepatic localizati<strong>on</strong> is the most frequent (63%), because the infestati<strong>on</strong> occurs by<br />

digestive way, and liver is the first filter <strong>on</strong> this way. Hydatid disease may have any<br />

localizati<strong>on</strong>. Cystic echinococcosis has public health importance not <strong>on</strong>ly in areas of<br />

endemicity but also in countries or regi<strong>on</strong>s without endemicity due to the migrati<strong>on</strong> of<br />

infected people and livestock exchanges.<br />

Keywords: Echinococcus granulosus, hepatic hydatic cyst (HHC).<br />

INTRODUCTION<br />

Human echinococcosis is a zo<strong>on</strong>otic infecti<strong>on</strong> caused by the tapeworm of the genus<br />

Echinococcus. Of the 4 known species of Echinococcus, 3 are of medical importance in<br />

humans. These are Echinococcus granulosus, causing cystic echinococcosis; Echinococcus<br />

multilocularis, causing alveolar echinococcosis; and Echinococcus vogeli. Echinococcus<br />

granulosus is the most comm<strong>on</strong> of the three. Echinococcus multilocularis is rare, but is the<br />

most virulent and Echinococcus vogeli is the most rare (Table 1) (Brunetti E, 2006).<br />

Table 1: Echinococcus Species<br />

Echinococcus Species Echinococcosis Diseases<br />

1. Echinococcus granulosus Cystic Echinococcosis (cystic hydatid disease)<br />

2. Echinococcus multilocularis Alveolar Echinococcosis<br />

3. Echinococcus vogeli Polycystic Echinococcosis<br />

AS 4. Echinococcus oligarthus Polycystic Echinococcosis<br />

AS=mal Species<br />

Incidence<br />

Echinococcosis is a very rare disease in northern Europe. The disease is endemic in the<br />

Balkan Area and in Eastern Europe. The endemic areas are the Mediterranean countries and<br />

the Middle East. The intensive endemic areas are the southern part of South America,<br />

Iceland, Australia, New Zealand and southern parts of Africa. The incidence of Cystic<br />

553

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