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Joint International Conference on Long-term Experiments ...

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4./ Discussi<strong>on</strong>s<br />

Botulism is a serious disease which not being treated leads to demise (Arn<strong>on</strong> et al, 2006,<br />

Mandell et al, 2005, Mayo Clinic, 2006). The historical study of the decays hotbeds<br />

prove the decrease in time of the number of the collective hotbeds, with the increase of<br />

the individual cases. In the present study 14 (48,27%) pers<strong>on</strong>s bel<strong>on</strong>g to the familial<br />

hotbeds, the rest of 15 (51,72%) ill people being individual cases of decay (Mandell et<br />

al, 2005; McLauchlin et al, 2006; WHO, 2006). It is also observed an increased<br />

incidence of botulism in Bihor county in the last 10 years, the maximum incidence<br />

being registered in 2004 with a total of 11 (37,93%) cases, fact that reveals the customs<br />

of preparing meat, fish and many other tinned food, frequently, incorrectly in precarious<br />

c<strong>on</strong>diti<strong>on</strong>s of hygiene.<br />

A feature of the present lot c<strong>on</strong>sists of the n<strong>on</strong>-recogniti<strong>on</strong> of the initial clinical<br />

table, 20 (68,96%) patients being hospitalized with different diagnoses in other medical<br />

services, being transferred in our service after a rigorous neurological exam and the<br />

exclusi<strong>on</strong> of the other neurological diseases; thus: 7 (24,13%) patients were formally<br />

hospitalized at Neurology and 1 (3,44%) case at Pediatry, digestive signs, marked<br />

asthenia and specific neurological signs, as well as the existence of <strong>on</strong>e or more<br />

members of the same family with characteristic symptomatology missing the initial<br />

examiners.<br />

The data from the literature point out a bigger frequency of botulism <strong>on</strong> men<br />

(60%) with the highest level of morbidity at 30-39 and 50-59 years (Mandell et a, 2005;<br />

Rebedea et al, 2000), unlike our lot where the report men/women tries to become equal<br />

with the highest level of morbidity at the group of age 15-24 years (from the category of<br />

pupils/students, with the frequency of the alimentary packs incorrectly preserved).There<br />

weren’t observed peculiar differences as c<strong>on</strong>cerns the provenience area of the patients<br />

or their level of educati<strong>on</strong>.<br />

Most of cases evolved as average clinical forms, the evoluti<strong>on</strong> being severe <strong>on</strong>ly in<br />

two cases, with the appearance of respiratory insufficiency because of respiratory<br />

muscular paralysis <strong>on</strong> a young woman patient of 20 years and of coma <strong>on</strong> a 3 year old<br />

girl, the clinical evoluti<strong>on</strong> being further favorable in both situati<strong>on</strong>s. The predominant of<br />

the average forms of the disease, as well as of the eradicators of pork meat involved in<br />

most of diseases, lead us to the associati<strong>on</strong> with the B type of exotoxin, frequent in<br />

Europe (Mandell et al, 2005; Rebedea et al, 2000), although the toxinopatia of the<br />

botulism cases couldn’t be made.<br />

A bigger frequency of the diseases in the m<strong>on</strong>ths of February and May is also<br />

correlated with the local customs ( the pig butchery in December, meat preservati<strong>on</strong> and<br />

that of other pork products being smoked during m<strong>on</strong>ths) and with the culinary customs<br />

for Easter.<br />

5./ C<strong>on</strong>clusi<strong>on</strong>s<br />

1. Botulism is a severe alimentary toxiinfecti<strong>on</strong> which, not being treated leads to<br />

demise; the preventi<strong>on</strong> of the decay c<strong>on</strong>sists of a harsh alimentary hygiene.<br />

2. The increased incidence of the decay (both under familial hotbeds and individual<br />

cases) in Bihor county because of the culinary customs specific to this geographic<br />

area.<br />

484

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