Joint International Conference on Long-term Experiments ...

2. botulism of inoculation-through the toxin’s penetration straight in the general flow
from the level of a wound contaminated with clostridies;
3. infantile botulism-the botulinic toxin being produced in vivo, by colonizing the
intestinal tract of the suckling, with Clostridium botulinum ( Arnon et al, 2006;
Brett et al, 2005).
2./ Objective:
Assessment of clinical-epidemiological parameters on patients with botulism,
hospitalized in the Clinical Hospital of infectious Diseases, Oradea between January
1997 – December 2006.
3./ Patients and methods
The retrospective study in 29 patients with botulism hospitalized in the Clinical
Hospital of Infectious Diseases, Oradea between January 1997 – December 2006, was
made on the base of registered data in the clinical observation papers of the patients.
There were analyzed the following parameters:
• demographic: age, sex, provenience areas;
• epidemiological: way of transmission, source of contamination;
• clinical: incubation, clinical forms of the disease, evolution under etiological
treatment.
The paraclinical confirmation of botulism was made through the test of specific
seroneutralization in the mouse.
3./ Results
In the period taken to be studied there were hospitalized in the Clinical Hospital of
Infectious Diseases Oradea, a number of 912 patients with alimentary toxiinfection, of
whom 29 patients were diagnosed with botulism (3.17% of the total cases of alimentary
toxiinfection). The incidence of the cases of botulism was as follows:
6
11
nr. Cases
0 5
Fig. nr.1. Incidence of cases
481
2
3
1
1
0
1
2
3
4
5
6
7
8
9
10