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Joint International Conference on Long-term Experiments ...

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The family doctors must be informed about the families where premature births,<br />

repeated aborti<strong>on</strong>s, malformed children or cases of sterility occurred, in order to<br />

perform an epidemiologic investigati<strong>on</strong> regarding Toxoplasma g<strong>on</strong>dii infecti<strong>on</strong>.<br />

Family planning offices as well as gynecologists must evaluate the possible<br />

toxoplasmic infecti<strong>on</strong> in future mothers.<br />

In Romania it is imperative to make the etiologic diagnosis by evidencing not <strong>on</strong>ly<br />

the specific IgM and IgG antibodies but also the antigenic structures which indicate the<br />

presence of living parasite inside the organism.<br />

REFERENCES<br />

1. J<strong>on</strong>es JL et all – C<strong>on</strong>genital toxoplasmosis a review, Obstet Gynecol Surv., 2001<br />

mai, 56(5): 296-305.<br />

2. Johns<strong>on</strong> LL. SCID mouse models <strong>on</strong> acute and relapsing chr<strong>on</strong>ic Toxoplasma<br />

g<strong>on</strong>dii infecti<strong>on</strong>s. Infect Immun. 1992;60:3719-3724.<br />

3. Kmiec K et all – C<strong>on</strong>genital toxoplasmosis in own studies, Wiad Parazytol,<br />

2001,47 Suppl 1:51-7<br />

4. Leport C, Remingt<strong>on</strong> JS. Toxoplasmose au cours du SIDA. Presse Med.<br />

1992;21:1165-1171.<br />

5. Mandell et all – Principles & Practice of Infectious Dieseases, 5 th editi<strong>on</strong> 2004,<br />

Toxoplasma G<strong>on</strong>dii, 2859-2882.<br />

6. Sinibaldi J, De Ramirez I. Incidence of c<strong>on</strong>genital toxoplasmosis in live<br />

Guatemalan newborns. Eur J Epidemiol. 1992;8:516-520.<br />

7. Subauste CS, de Waal Malefyt R, Fuh F. Role of CD80 (B7.1) and CD86 (B7.2) in<br />

the immune resp<strong>on</strong>se to an intracellular pathogen. J Immunol. 1998;160:1831-<br />

1840.<br />

8. Swartzberg JE, Remingt<strong>on</strong> JS. Transmissi<strong>on</strong> of Toxoplasma. Am J Dis Child.<br />

1995;129:777-779.<br />

9. Tirard V, Niel G, Rosenheim M, et al. Diagnosis of toxoplasmosis in patients with<br />

AIDS by isolati<strong>on</strong> of the parasite from the blood. N Engl J Med. 1991;324:632.<br />

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