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<strong>IMS</strong> COM PANY PRO FILES TAKEDA<br />
BESTCALL (cefmenoxime), an in ject able third-gen er a tion cephalosporin an ti bi otic, was launched in Ja -<br />
pan by orig i na tor Takeda in 1983. Roche also mar kets it in Ja pan as Bestcall Roche. It is mar keted in<br />
Ger many and Aus tria by Takeda Pharma as Tacef. Han Il is the li censee for South Ko rea. Senju, Grelan<br />
and Kyorin sell oph thal mic versions in Japan.<br />
FAMVIR (famciclovir) is the in ac tive prodrug of penciclovir, which is ef fec tive against her pes sim plex vi -<br />
rus types 1 and 2. Famciclovir was ap proved for her pes zoster (shin gles) in the UK in De cem ber 1993 and<br />
was launched in the UK, its first mar ket, in Jan u ary 1994. Famciclovir has since been mar keted in the USA<br />
(July 1994) and in over 30 other coun tries worldwide.<br />
Li cens ing: In Sep tem ber 2006, TAP re ported that it had signed a co-pro mo tional agree ment with<br />
Novartis (Swit zer land) for famciclovir in the USA. Un der the terms of the agree ment, TAP was re spon si ble<br />
for pro mot ing famciclovir to ob ste tri cians and gy ne col o gists within the USA. Fur ther de tails of the agree -<br />
ment were not dis closed. In May 2008, Takeda and Abbott con cluded their TAP jv with Takeda re ceiv ing<br />
rights to the product.<br />
FIRSTCIN (cefozopran), a semisynthetic, broad-spec trum, parenteral cephalosporin an ti bi otic, was<br />
launched in Ja pan in 1995 by orig i na tor Takeda and li censee Lederle (now part of Wyeth). Firstcin is par -<br />
tic u larly ef fec tive against se vere in fec tions caused by staph y lo cocci and enterococci in<br />
immunocompromised pa tients. It has been ap proved for pe di at ric use and men in gi tis. It will not com pete<br />
against Takeda’s Pansporin as it is rec om mended for in fec tions that do not respond to Pansporin.<br />
Sales/An a lyst Com ment: With sales of Yen6.4 bil lion re ported in fis cal 2007 (end ing March 2008),<br />
Mor gan Stan ley an a lysts (Au gust 2008) fore cast a de cline in sales to Yen6 bil lion by the year to March<br />
2013.<br />
GLOVENIN (im mu no glob u lin base), a polyvalent in tra ve nous im mu no glob u lin used to treat se vere in -<br />
fec tions and im mu no de fi ciency syndromes.<br />
Sales/An a lyst Com ment: With sales of Yen8.8 bil lion re ported in fis cal 2007 (end ing March 2008), up<br />
from Yen8.6 bil lion the pre vi ous year, Mor gan Stan ley an a lysts (Au gust 2008) fore cast a slight de cline in<br />
sales to Yen8.5 bil lion by the year to March 2013.<br />
PANSPORIN (cefotiam), an in ject able cephalosporin an ti bi otic, was first launched by Takeda in Ja pan in<br />
1981. In 1983, Takeda launched Pansporin in the Phil ip pines and Thai land as Ceradolan, then in 1988 it<br />
was launched in Hong Kong, also as Ceradolan.<br />
In Sep tem ber 2008 Takeda filed a suit against Taiyo Yakuhin who man u fac tures Pansporin, de mand ing<br />
dam ages of Yen2.8 bil lion claim ing its qual ity con trol sys tem was de fi cient af ter it failed to re call all vi als<br />
(in which glass was found) from the market.<br />
Li cens ing: Pansporin was li censed to Ciba for world wide mar ket ing. Ciba (now part of Novartis, Swit zer -<br />
land) has launched it in a num ber of coun tries as Halospor, in clud ing Ger many, the Neth er lands and Ma -<br />
lay sia. Li censee Han Il launched it in South Ko rea in 1983. In 1989, it was ap proved for US mar ket ing as<br />
Ceradon, but has never been launched in North Amer ica and Takeda is not de vel op ing the oral form,<br />
Pansporin T (re fer to drug record) in the USA.<br />
Sales/An a lyst Com ment: With re ported sales of Yen8.4 bil lion in fis cal 2007 (end ing March 2008),<br />
Mor gan Stan ley an a lysts (Au gust 2008) fore cast a de cline in sales to Yen7.0 bil lion by the year to March<br />
2013.<br />
PANSPORIN T (cefotiam hexetil), an oral ver sion of the cephem an ti bi otic Pansporin, was launched in<br />
Ja pan in 1990. In 1993, it was launched in France by Takeda as Taketiam in part ner ship with Roussel<br />
Uclaf (now part of sanofi-aventis, France), which launched it as Texodil. Li censee Cheil launched it in<br />
© 2009 <strong>IMS</strong> Health In cor po rated or its af fil i ates Page 52