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<strong>IMS</strong> COM PANY PRO FILES TAKEDA<br />
Takeda was fined Euro37.1 mil lion by the EC Com mis sion over vi ta min price-fix ing be tween 1989 and<br />
1999. The to tal fine of Euro855.2 mil lion was the larg est ever im posed on com pa nies op er at ing a car tel in<br />
the EC, which in cluded Roche, BASF, and Daiichi Pharmaceuticals.<br />
Takeda be gan con struc tion of a new Yen17 bil lion genomics R&D fa cil ity in Tsukuba Ja pan, ded i cated to<br />
the anal y sis of gene and pro tein func tion and re gen er a tive gene re search, and speed ing up the de vel op -<br />
ment of genome-based drugs.<br />
TAP Phar ma ceu ti cal Prod ucts pleaded guilty to a crim i nal charge and agreed to pay the larg est ever crim i -<br />
nal fine in a health care fraud case, as in ves ti ga tions con tin ued re gard ing pre scrip tion drug scams and the<br />
il le gal mar ket ing of its anticancer drug Lupron. The com pany agreed to pay $875 mil lion to re solve crim i -<br />
nal and civil charges that it fraud u lently priced and mar keted the prostate cancer drug.<br />
Takeda and Nip pon A&L an nounced that they reached a tie-up agree ment re gard ing Takeda’s syn thetic<br />
rub ber la tex busi ness on July 1. The two com pa nies plan to sign an agree ment which trans fers Takeda’s<br />
syn thetic rub ber la tex busi ness to Nippon A&L.<br />
TAP Phar ma ceu ti cal Prod ucts (a jv be tween Abbott and Takeda) signed a co-pro mo tion deal with Sol vay<br />
(Bel gium) over the Sol vay drug AndroGel (tes tos ter one). Sol vay ini tially ex pected sales of $50 mil lion,<br />
but raised its fore cast to $100 mil lion af ter its Unimed Pharmaceuticals unit signed the co-pro mo tion deal<br />
with TAP.<br />
Takeda Pharmaceuticals North Amer ica, and Lilly an nounced they are un der writ ing and ed u ca tional pro -<br />
gram called Part ners Against In su lin Re sis tance. The ini tia tive is de signed to pro mote aware ness about<br />
in su lin re sis tance and its role in Type 2 di a be tes and re lated com pli ca tions, such as cardiovascular<br />
disease.<br />
Takeda in vited ap pli ca tions for an early re tire ment pro gram sched uled to start in April 2003. The pro gram<br />
is open to work ers aged 35 or over and is pri mar ily aimed at of fer ing var i ous op tions to em ploy ees, in -<br />
clud ing job changes, rather than a re duc tion of la bor ex penses. The com pany has not set a tar get for job<br />
cuts under the program.<br />
TAP con firmed that it was be ing in ves ti gated by the Texas state at tor ney over the mar ket ing and pric ing<br />
of Lupron. TAP is also be ing ex am ined by the US Jus tice De part ment for prac tices such as en cour ag ing<br />
phy si cians to bill in sur ance com pa nies for free sam ples of Lupron (at $400 to $550 per in jec tion). The in -<br />
ves ti ga tion be gan in 1998 in Boston and ru mors of a set tle ment spread in early 2001 af ter TAP said it was<br />
chan nel ing money into a le gal re serve fund. An un em ployed woman from Saitama Pre fec ture was sen -<br />
tenced to two-and-a-half years in jail af ter threat en ing to con tam i nate Takeda’s eye wash prod ucts. Her<br />
ac tions were said to have caused Takeda Yen150 mil lion in losses af ter it was forced to re call its Mytear<br />
SG and Catalin K prod ucts. Ms Fujino also black mailed another Japanese pharmaceutical company,<br />
Santen.<br />
Takeda said it planned to outsource 50% of its phar ma ceu ti cal out put by 2003 (cur rently 30%). The tar -<br />
get will be achieved through the con sol i da tion of pro duc tion of hos pi tal drugs and the clo sure of a plant in<br />
Kanagawa Pre fec ture re spon si ble for man u fac tur ing in ject able drugs. It was orig i nally meant to close in<br />
2005, but this has now been brought for ward to De cem ber 2003. Takeda’s pro duc tion will be shifted to<br />
other com pa nies, both do mes tic and in ter na tional. The com pany said it was tak ing the step due to slow<br />
growth in the do mes tic mar ket and grow ing com pe ti tion from abroad. Hos pi tal drug man u fac ture will be<br />
cen tered on Takeda’s plants in Osaka and Yamaguchi. Its num ber of em ploy ees in volved in pro duc tion<br />
will fall to 700 in 2005, from 1,200, already 25% down from 1998.<br />
Takeda Amer ica sold its en tire stake in Takeda Vi ta min & Food USA to BASF. The price was not dis closed.<br />
The sale fol lowed the July 2000 agree ment be tween the two com pa nies to merge their bulk vi ta min op er -<br />
a tions.<br />
© 2009 <strong>IMS</strong> Health In cor po rated or its af fil i ates Page 116