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<strong>IMS</strong> COM PANY PRO FILES TAKEDA<br />
420 em ploy ees (in clud ing its four 100% sub sid iar ies). The new ven ture is ex pect ing con sol i dated sales of<br />
around Yen36 bil lion. The ar range ment was ap proved by both Jap a nese reg u la tors and the EC, on the ba -<br />
sis that Takeda’s busi ness was largely domestic and Sumitomo’s was largely international.<br />
Takeda an nounced plans to sell its 32.5% hold ing in Shimizu Seiyaku to Suzuyo (Ja pan). Takeda will end<br />
its sales con tract with Shimizu Seiyaku at the end of March 2003. The moves fol low an agree ment by Aji -<br />
no mo to to ac quire Shimizu Seiyaku and its wholly-owned sub sid iary Shimizu Med i cal by the end of 2002.<br />
Takeda was re quired to pay Yen500 mil lion in pen alty taxes fol low ing in cor rect book ing of in come and ex -<br />
penses dur ing 2000 and 2001.<br />
A for mer TAP sales rep re sen ta tive pleaded guilty to a charge of vi o lat ing the US pre scrip tion Drug Mar ket -<br />
ing Act in re spect of Lupron (leuprorelin). The rep re sen ta tive had failed to ob tain a writ ten re quest from a<br />
phy si cian for free sam ples, and could face a jail sen tence plus a $100,000 fine. By July 2002, 14 TAP em -<br />
ploy ees in clud ing three se nior ex ec u tives had been charged since the start of the Fed eral in ves ti ga tion<br />
into Lupron-related fraud.<br />
TPNA (Takeda Pharmaceuticals North Amer ica) re struc tured its se nior ex ec u tive team and ap pointed a<br />
new Pres i dent, Mark Booth, to take man age ment re spon si bil ity for all TPNA’s business.<br />
Con tracts be tween Takeda and Ad vance PCS, a US phar macy ben e fit man age ment com pany, be came<br />
the sub ject of an in ves ti ga tion by the Phil a del phia US At tor ney’s Of fice in ves ti gat ing whether Ad vance<br />
PCS prop erly re ported re bates to Fed eral Em ployee Health Ben e fit pro grams. Takeda is one of 14 man u -<br />
fac tur ers whose contracts are being examined.<br />
Takeda an nounced it is to sell its syn thetic rub ber la tex busi ness to Nip pon AL, a jv be tween Sumitomo<br />
Chem i cal (Ja pan) and Mitsui Chem i cals (Ja pan). For mal trans fer was due in October 2002.<br />
TAP ex plained that it was not the tar get of an in ves ti ga tion that re sulted in sev eral US health ben e fit man -<br />
age ment com pa nies re ceiv ing re ceived Fed eral sub poe nas in April and May 2002. Some of the com pa nies<br />
were asked for doc u ments re lat ing to their relationship with TAP.<br />
TAP’s Phar ma ceu ti cal Eth ics and Com pli ance Of fi cer agreed to chair the US Health Care Com pli ance As so -<br />
ci a tion task force to de velop mea sure ments to eval u ate the ef fec tive ness of cor po rate com pli ance pro -<br />
grams. As part of its set tle ment of crim i nal and civil charges re lated to Lupron pro mo tion, TAP agreed to<br />
an ex ten sive corporate integrity program<br />
Takeda an nounced plans to in vest around Euro80 mil lion in a new bulk phar ma ceu ti cal pro duc tion plant<br />
in Clondalkin, Ire land. It will be Takeda’s first such fa cil ity out side Ja pan. Op er a tions are sched uled to be -<br />
gin in 2004, when the plant will ini tially pro duce Actos (pioglitazone) for Eu ro pean and US mar kets and<br />
new com pounds for clin i cal tri als. Takeda al ready has a for mu la tion and pack ag ing plant in Ire land. The<br />
two sites will be run as sep a rate com pa nies, with the new bulk plant tak ing over the Takeda Ire land<br />
name. The ex ist ing pack ag ing and for mu la tion site will be renamed Takeda Ireland Products.<br />
• Year: 2001<br />
The Jap a nese Phar ma ceu ti cal Group (JPG), was set up in the UK to rep re sent the views of 10 R&D Jap a -<br />
nese com pa nies, in clud ing Takeda, which sell branded med i cines to the NHS.<br />
Takeda an nounced its in ten tion to es tab lish an in vest ment com pany in the USA, called Takeda Re search<br />
In vest ment (TRI) on the west coast, which will pro vide fund ing for bio tech nol ogy start-ups and<br />
early-stage ven tures con duct ing re search or de vel op ing tech nol o gies for in no va tive drug dis cov ery. TRI<br />
was given an in vest ment fund of $100 mil lion and will take stakes in tar get com pa nies to ac cel er ate<br />
Takeda’s own re search activities in the area by 2005.<br />
© 2009 <strong>IMS</strong> Health In cor po rated or its af fil i ates Page 115