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<strong>IMS</strong> COM PANY PRO FILES TAKEDA<br />
<strong>Company</strong>/Organization Date Area of<br />
Collaboration<br />
Takeda, Hitachi Ltd. and<br />
Juntendo University<br />
Faculty of Medicine<br />
Terms of Agreement<br />
1999 SNPs A collaboration into the identification of<br />
SNPs. The project is being run under the<br />
auspices of the Japan Biotechnology<br />
Industry Consortium. Lasting for 1 year,<br />
the project will focus on allergic diseases.<br />
Takeda will use the information in its drug<br />
discovery efforts. Hitachi will build a<br />
large-scale, rapid SNP identification<br />
system. Some 200 patients with atopic<br />
dermatitis, and 100 healthy controls, will<br />
be used to identify at least 10 groups of<br />
cytokines and cytokine receptor genes.<br />
Novo Nordisk 1996 Diabetes Research deal for the development of<br />
compounds for diabetes. The goal is to<br />
identify orally active drugs for controlling<br />
blood glucose in Type 2 diabetes. NN will<br />
contribute its expertise relating to<br />
receptors for blood glucose regulation.<br />
Takeda will provide a library of small<br />
molecules with affinity for these receptors.<br />
Human Genome Sciences,<br />
Glaxo SmithKline<br />
1995 Genome data,<br />
combinatorial<br />
chemistry<br />
© 2009 <strong>IMS</strong> Health In cor po rated or its af fil i ates Page 107<br />
Takeda gained access to HGS’ human<br />
genome database and SB’s combinatorial<br />
chemistry technology. In 2002 Takeda<br />
exercised its option to develop and<br />
commercialize mapatumumab in Japan;<br />
an option fee has been paid and Takeda<br />
will also pay milestones and royalties if the<br />
compounds are marketed in Japan