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<strong>IMS</strong> COM PANY PRO FILES TAKEDA<br />
<strong>Company</strong>/Organization Date Area of<br />
Collaboration<br />
Albany Molecular<br />
Research<br />
Terms of Agreement<br />
2002 Drug discovery AMRI and Takeda have agreed a 1 year<br />
basic drug discovery program involving<br />
identification by AMRI of small molecule<br />
candidates for a range of undisclosed<br />
disorders. Takeda will provide funding,<br />
milestone payments and royalties for<br />
products resulting from the research.<br />
Santarus 2002 Lifecycle<br />
development of<br />
gastrointestinal drugs<br />
Oxford Centre for<br />
Diabetes, Endocrinology<br />
and Metabolism<br />
Specialized Health<br />
Products International<br />
TAP in-licensed rights to manufacture and<br />
market products in the USA using<br />
Santarus technology to expand the<br />
lifecycle of existing products. TAP initially<br />
paid $8m and may pay up to $100m if<br />
new drugs are successfully<br />
commercialized; $10m milestone paid in<br />
2005. Takeda exercised its right to<br />
terminate the agreement in January 2006.<br />
2002 Diabetes treatments A 5 year partnership agreement was<br />
signed. Takeda has joined the board of the<br />
center and donated Yen600m to support<br />
construction of the second phase of its<br />
research facilities.<br />
2002 Syringe safety TAP and SHPI agreed a deal to use SHPI’s<br />
proprietary safety needle device for TAP’s<br />
pre-filled syringe products. SHPI will<br />
receive reimbursement for R&D expenses,<br />
milestone and royalty payments.<br />
Gene Logic 2002 Genomics database Takeda subscribed to Gene Logic’s<br />
BioExpress database for use in its<br />
genomics-based drug target discovery<br />
programs. Expanded in 2003, giving<br />
access to complete dataset, allowing<br />
assessment of full range of human tissues,<br />
animal, and cell lines. Subscription<br />
extended in 2005 through 2006; Takeda<br />
also gained perpetual license to data<br />
existing.<br />
Human and Animal Bridge<br />
(HAB) Discussion Group<br />
Biomolecular Engineering<br />
Research Institute<br />
2001 Database creation Research into a drug interaction database<br />
using human liver microsomes.<br />
2001 Biochemistry Research into the application of<br />
biomolecular functions.<br />
© 2009 <strong>IMS</strong> Health In cor po rated or its af fil i ates Page 104
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