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<strong>IMS</strong> COM PANY PRO FILES TAKEDA<br />
<strong>Company</strong>/Organization Date Area of<br />
Collaboration<br />
Array BioPharma 2004 Diabetes and<br />
hypertension<br />
Terms of Agreement<br />
The companies will utilize the US firm’s<br />
technologies to develop improved<br />
candidate drugs based on compounds<br />
discovered by Takeda. The Japanese firm<br />
will own the intellectual property<br />
associated with the modified agents and<br />
will pay Array compensation linked to the<br />
latter’s contributions, as well as a fixed<br />
percentage of sales for any drug that<br />
enters the market.<br />
Ligand Pharmaceuticals 2004 Drug development Under the terms of the agreement, Ligand<br />
provided notice to TAP of its intention to<br />
exercise its option to select within 90 days<br />
one compound and a backup for<br />
development. TAP retains an option to<br />
negotiate to co-develop and co-promote<br />
compounds with Ligand up to the end of<br />
phase II. Ligand earned a $1 million<br />
milestone payment from TAP as a result.<br />
Ligand announced an extension of the<br />
collaboration in December 2004 through<br />
to June 2006.<br />
University of Tokyo 2004 Drug<br />
development/disease<br />
prevention<br />
Lectus Therapeutics 2004 Small-molecule ion<br />
channels<br />
Takeda joined a medical consortium<br />
(including Tanabe, AnGes MG, and<br />
Terumo) project which aims to provide a<br />
base and incubation facilities for research<br />
into new drugs, disease prevention, and<br />
health-related services. Terms of the deal<br />
were undisclosed at the time of writing.<br />
Takeda Research Investment is funding<br />
Lectus’ drug discovery and development<br />
programs. Specific terms and conditions of<br />
the deal were undisclosed at the time of<br />
writing.<br />
Innogenetics 2004 Alzheimer’s disease Innogenetics licensed patents rights to<br />
Takeda’s beta-amyloid antibodies for<br />
research and diagnostic use. Financial<br />
terms of the deal were undisclosed at the<br />
time of writing.<br />
© 2009 <strong>IMS</strong> Health In cor po rated or its af fil i ates Page 102