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IMS Company Profiles - Report Buyer

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<strong>IMS</strong> COM PANY PRO FILES TAKEDA<br />

<strong>Company</strong>/Organization Date Area of<br />

Collaboration<br />

ARIUS Research 2006 FunctionFIRST<br />

technology platform<br />

Paradigm Therapeutics<br />

(UK)<br />

2005 Drug discovery (CNS<br />

disorders)<br />

Terms of Agreement<br />

ARIUS Research signed a three-year<br />

collaborative agreement with Takeda to<br />

discover treatments for human disease<br />

using ARIUS’s FunctionFIRST technology<br />

platform. Under the terms of agreement<br />

Takeda will pay an upfront technology<br />

access fee of $2 million ($1 million each in<br />

cash and equity investment, respectively)<br />

as well as research funding for three<br />

years. Confirmed ongoing by Takeda in<br />

2008.<br />

3-year deal to access novel proprietary<br />

therapeutic targets identified by Paradigm<br />

for selected CNS disorders. Takeda will<br />

pay up-front fees and milestones totaling<br />

up to $18m for each product and then<br />

sales royalties.<br />

Flamel Technologies 2004 New formulations TAP licensed the worldwide rights for<br />

Flamel’s Micropump controlled-release<br />

technology for the oral administration of<br />

lansoprazole. TAP will pay costs of further<br />

development, testing, regulatory approval,<br />

and marketing of the new formulation.<br />

HTG 2004 New drug candidates HTG will use its multiplexed ArrayPlate<br />

technology to screen samples provided by<br />

Takeda and gather critical information on<br />

the interplay of genes in biological<br />

systems. HTG will deliver high-quality,<br />

multiplexed gene expression test results to<br />

assist Takeda to identify promising new<br />

drug candidates. Financial terms were not<br />

disclosed. In 2006 Array BioPharma<br />

advanced two lead compounds into<br />

preclinical studies, triggering milestone<br />

payments from Takeda.<br />

© 2009 <strong>IMS</strong> Health In cor po rated or its af fil i ates Page 101

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