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STAT 689 Advanced Bayesian Modeling and Computation

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<strong>STAT</strong> <strong>689</strong> <strong>Advanced</strong> <strong>Bayesian</strong> <strong>Modeling</strong> <strong>and</strong> <strong>Computation</strong><br />

Instructor Bani Mallick<br />

Office 459B Blocker<br />

Phone 845-1275<br />

Office Hours 3-4, T/R<br />

Email bmallick@stat.tamu.edu<br />

TA Shubhankar Ray<br />

Office 459F Blocker<br />

Phone 458-0570<br />

Office Hours —<br />

Email sray@stat.tamu.edu<br />

Course website http://www.stat.tamu.edu/˜sray/stat<strong>689</strong>.html<br />

Prerequisites <strong>STAT</strong> 608, 613, 632 or approval of instructor.<br />

Description of course<br />

This is a research course intended for a mixed audience of graduate students in statistics <strong>and</strong> other<br />

fields who plan to use <strong>Bayesian</strong> methods in their own research. The topics covered will provide a<br />

broad exposure to the basic concepts, methodology <strong>and</strong> applications in Bioinformatics, Biostatistics,<br />

Signal Processing, Machine Learning <strong>and</strong> related areas. Students are required to work on a project<br />

with emphasis on h<strong>and</strong>s-on <strong>Bayesian</strong> computation in Matlab/BUGS; <strong>and</strong> present it at the semester<br />

end.<br />

References<br />

1. Gelman, Carlin, Stern <strong>and</strong> Rubin, <strong>Bayesian</strong> Data Analysis, CRC Press, 2003. 2. Denison,<br />

Holmes, Mallick <strong>and</strong> Smith, <strong>Bayesian</strong> methods for Nonlinear Classification <strong>and</strong> Regression, Wiley,<br />

2002. 3. Hastie, Tibshirani <strong>and</strong> Friedman, The Elements of Statistical Learning, Springer, 2001. 4.<br />

Bernardo <strong>and</strong> Smith, <strong>Bayesian</strong> Theory, Wiley, 1994.<br />

Course Outline*<br />

1. Hierarchical Models. Prior distributions, <strong>Bayesian</strong> Inference, Model assessment.<br />

2. <strong>Bayesian</strong> <strong>Computation</strong>. Asymptotic Methods, Non-iterative, Markov Chain, Sequential<br />

<strong>and</strong> Reversible Jump Monte Carlo methods.<br />

3. Model Criticism <strong>and</strong> Selection. Model Choice <strong>and</strong> Model Mixing.<br />

4. <strong>Bayesian</strong> Mixture Models <strong>and</strong> Variable Selection.<br />

5. <strong>Bayesian</strong> Classification <strong>and</strong> Regression. Linear <strong>and</strong> Non-linear Regression, Support<br />

Vector Machines, Partition Models, Classification <strong>and</strong> Regression Trees.<br />

6. Statistical Learning. Principal component analysis (PCA), Clustering, Kernel methods,<br />

Support Vector Machines.<br />

7. Spatial Models <strong>and</strong> Markov R<strong>and</strong>om Fields.<br />

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8. Analysis of Functional Data.<br />

9. Applications. Bioinformatics (Microarray Data Analysis, Functional Genomics, Sequence<br />

Alignment, Hidden Markov Models, etc), Biostatistics (Survival Analysis, Longitudinal Analysis),<br />

Signal Processing, Spatial <strong>Modeling</strong>.<br />

* Course Material can be changed any time at the discretion of the instructor.<br />

Grading Policy<br />

The course grade will be based on some HWs (20<br />

Statement of Plagiarism<br />

As commonly defined, plagiarism consists of passing of as ones own ideas, words, writing, etc.,<br />

which belong to another. In accordance with this definition, you are committing plagiarism if you<br />

copy the work of another person <strong>and</strong> turn it in as your own, even if you should have the permission<br />

of that person. Plagiarism is one of the worst academic sins, for the plagiarist destroys the trust<br />

among colleagues without which research cannot be safely communicated. If you have any questions<br />

regarding plagiarism, please consult the latest issue of the Texas A&M University Student Rules,<br />

under the section Scholastic Dishonesty.<br />

Statement of Disabilities<br />

The Americans with Disabilities Act (ADA) is a federal anti-discrimination statute that provides<br />

comprehensive civil rights protection for persons with disabilities. Among other things, this legislation<br />

requires that all students with disabilities be guaranteed a learning environment that provides<br />

for reasonable accommodation for their disabilities. If you believe you have a disability requiring<br />

an accommodation, please contact the Offce of Support Services for Students with Disabilities in<br />

Room 126 of the Koldus Student Services Building. The phone number is 845-1637.<br />

Copyright Notice<br />

The h<strong>and</strong>outs used in this course are copyrighted. By h<strong>and</strong>outs, I mean all materials generated<br />

for this class including syllabi, exams, in-class material, <strong>and</strong> computer examples. Because these<br />

materials are copyrighted, you do not have the right to copy the h<strong>and</strong>outs, unless I expressly grant<br />

permission.<br />

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