The Great Dane - Breed Nutrition - Royal Canin

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References A food to improve digestive security 1. Bliss DZ, Jung HJ, Savik K et al. – Supplementation with dietary fiber improves fecal incontinence. Nurs Res 2001; 50(4): 203-213. 2. Bright RM - New perspectives on GDV. BSAVA Congress 2003, Scientific Proceedings: 413-415. 3. German A, Zentek J - Affections digestives les plus fréquentes : rôle de la diététique. In: Encyclopédie de la Nutrition Clinique Canine; Royal Canin (Aniwa SAS ed), 2006: 92- 127. 4. Glickman LT, Glickman NW, Perez CM et al. – Analysis of risk factors for gastric dilatation and dilatation-volvulus in dogs. J Am Vet Med Ass 1994 ; 204(9 ): 1465-1471. 5. Glickman LT, Glickman NW, Schellenberg DB et al. – Non-dietary risk factors for gastric dilatation-volvulus in large and giant breed dogs. J Am Vet Med Ass 2000; 217(10): 1492-1499. 6. Hernot DC, Biourge VC, Martin LJ et al. – Relationship between total transit time and faecal quality in adult dogs differing in body size. 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Weber MP, Hernot D, Nguyen PG et al. – Effect of size on electrolyte apparent absorption rates and fermentative activity in dogs. J Anim Physiol Anim Nutr (Berl) 2004; 88(9-10): 356-65. 17. Weber M, Martin L, Biourge V et al. – Influence of age and body size on the digestibility of a dry expanded diet in dogs. J Anim Physiol Anim Nutr 2003; 87: 1-11. 20. Lauten SD, COX NR, Brawner WR Jr et al. – Use of dual energy x-ray absorptiometry for noninvasive body composition measurements in clinically normal dogs. Am J Vet Res 2001; 62(8): 1295-1301. 21. Adebowale A, Du J, Liang Z et al. – The bioavailability and pharmacokinetics of glucosamine hydrochloride and low molecular weight chondroitin sulfate after single and multiple doses to beagle dogs. Biopharm Drug Dispos 2002; 23(6): 217-225. 22. Baasler C, Rovati L, Franchimont P – Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritic articular cartilage in vitro. 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Deeb BJ, Wolf NS - Studying longevity and morbidity in giant and small breeds of dogs. Vet Med 1994; Suppl Life Expectancy, 89(7): 702-713. 29. Hazewinkel HAW, Goedegebuure SA, Poulos PW et al - Influences of chronic calcium excess on the skeletal development of growing Great Danes. J Am Anim Hosp Assoc 1985; 21: 337-391. 38. Alroy J, Rush JE, Freeman L – Inherited infantile dilated cardiomyopathy in dogs: genetic, clinical, biochemical, and morphologic findings. Am J Med Genet. 2000; 95(1): 57-66. 39. Costa ND, Labuc RH – Case report: efficacy of oral carnitine therapy for dilated cardiomyopathy in boxer dogs. J Nutr. 1994; 124(12 Suppl): 2687S-2692S. 40. Deeb BJ, Wolf NS – Studying longevity and morbidity in giant and small breeds of dogs. Vet Med 1996; 61(6:Suppl): 702-713. 41. Hanichen T - Cardiomyopathy in dogs and cats. Tierarztliche Umschau 1986; 41: 7: 467-474. Nutrition that targets the joints Taurine and L-carnitine: nutrients for heart function 30. Hazewinkel HA, Theyse LF, Wolvekamp WT et al. – The influence of dietary omega-6: Omega -3 ratio on lameness in dogs with osteoarthrosis of the elbow joint. In: Recent Advances in Canine and Feline Nutrition vol II (ed GA Reinhart & DP Carey); Orange Frazer Press, Wilmington (OH), 1998: 325-336. 31. Hedhammar A, Wu F, Krook L et al - Overnutrition and skeletal disease; an experimental study in growing Great Danes dogs. Cornell Vet 1974; 64 (Suppl 5), 1 : 59. 32. Johnston KA, Hulse DA, Hart RC - Effects of on orally administered mixture of chondroitin sulfate, glucosamine hydrochloride and manganese ascorbate on synovial fluid chondroitin sulfate 3B3 and 7D4 epitope in a canine cruciate ligament transection model of osteoarthritis. Osteoarthritis Cartilage 2001; (1): 14-21. 33. LaFond E, Breur GJ, Austin CC – Breed susceptibility for developmental orthopedic diseases in dogs. J Am Anim Hosp Assoc 2002; 38(5): 467-477. 34. McLaughlin R - Management of chronic osteoarthritic pain. 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Basic Res Cardiol 1993; 88(4): 362- 70. 27
Scientific glossary Colon: one of the three segments of the large intestine, between the caecum (small in dogs) and the rectum. The colon is where water is reabsorbed. It is home to an abundant bacterial flora. Chondroitin (sulphate): one of the main glycosaminoglycans (GAGs), essential components of cartilage. Body composition: distribution of weight between lean mass (all heterogeneous liquids, minerals, glycogen and protein in the body) and fat mass, where energy is stored as fat. Digestibility: degree to which a food or nutrient is absorbed during its transit through the small intestine. Digestibility determines the energy value of the food in question. EPA/DHA: omega 3 long-chain fatty acids known to curb the inflammatory activities of omega 6 fatty acid derivatives; abundant in fish oils. FOS (fructo-oligosaccharides): fermentable fibre that facilitates the growth of a beneficial bacterial flora (lactobacilli and bifidus) at the expense of pathogenic bacteria (salmonella, clostridium). Glucosamine: glycosaminoglycan (GAG): precursor that stimulates the production of cartilage cells. Gluten: protein fraction of some cereals: wheat, rye, barley or oats. Wheat gluten contains 80-82% highly digestible protein that is rich in glutamine, an important amino acid for the digestive mucosa. L-carnitine: transports fatty acids and stimulates the use of fats. It facilitates the passage of fatty acids into the mitochondria, the cell’s energy generation plant. Intestinal permeability: in large dogs, the junctions between the cells of the intestinal mucosa can allow the passage by diffusion of some ions, attracted by a higher concentration gradient in the intestinal lumen. LIP: Royal Canin label guaranteeing very high protein digestibility (> 90%). Taurine: a sulphur-amino acid, a major component of immune cells, concentrated in the retina and the heart. Also functions as an antioxidant. 28 Key innovations for dogs in the history of Royal Canin A history of commitment to developing its knowledge of and respect for the needs of small, medium and large breeds 1980 - Launch of AGR, the first food for large-breed puppies and the first “cynotechnic” range dedicated to breeders. 1990 - Launch of the first RCCI high-nutrition foods for dogs on the specialist circuit, including PR27, specially formulated for small dogs. 1997 - Launch of RCCI SIZE, the world’s first nutritional programme for dogs to take into account age, activity and especially the size of the various breeds. 1999 - Launch of the first weaning food, STARTER, for use by breeders. - Launch of Vet Size, the first nutritional programme for small, medium and large breeds, for exclusive use by veterinarians. 2000 - Launch of SIZE NUTRITION, 3 nutritional programmes adapted to the needs and physiological characteristics of small, medium and large breeds. 2001 - Launch of GIANT, the first nutritional programme specially developed for large breeds (> 45 kg). 2002 - Launch of the first immunity programme that helps support the strength of the dog’s natural defences during every stage of its life (MEDIUM IMMUNITY PROGRAM). - Royal Canin innovates once again, with a made-to-measure food for Yorkshire Terriers: MINI YORKSHIRE 28. 2003 - Nutritional precision is harnessed in GERMAN SHE- PHERD 24 for the breed that has been the brand’s emblem from the first day and LABRADOR RETRIEVER 30. 2004 - The launch of the Size Health Nutrition range provides new nutritional keys for the growth stage of large and giant breeds: MAXI BABY DOG and GIANT BABY DOG. - The launch of made-to-measure foods specifically developed for two small breeds: POODLE 30 and DACH- SHUND 28. - Launch of the best-balance foods BOXER 26 and BULL- DOG 24. 2005 - The breeders’ range is augmented with two new foods: ANŒSTRUS 22 and HT 42 D, for breeding bitches. - GERMAN SHEPHERD JUNIOR completes the nutritional programme dedicated to the German Shepherd. 2006 - LABRADOR JUNIOR completes the nutritional programme dedicated to the Labrador Retriever. - The Mini range for small dogs is augmented with: - MINI JUNIOR ULTRA SENSIBLE and DACHSHUND JUNIOR for puppies. - MINI INDOOR, SHIH TZU 24 AND CHIHUAHUA 28 for adults. - Launch of the made-to-measure food MINIATURE SCHNAUZER. 2007 - Launch of the made-to-measure food: GREAT DANE 23. 29 Made by Aniwa S.A.S. on behalf of Royal Canin Publication: Direction Communication Royal Canin Group/Aimargues. France Editor/Supervisor: Pascale Pibot (Scientific Editions Manager) Publishing contact: Marie-Laure Rémy-Néris Production: Diffomédia Paris Printed in the EU © Royal Canin 01/2007 Artistic direction: Élise Langellier, Guy Rolland © Illustrations: Diffomédia/Élise Langellier, Mickaël Masure Editorial coordination: Valérie de Leval Cover photo: Voltaire des Terres axonaises © J.-M. Labat
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The Great Dane - Breed Nutrition - Royal Canin

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