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$ Millions<br />

But Few “Big Pharma-Size” Successes<br />

9<br />

Sales Ramp Up of Selected Branded Pain Meds Introduced<br />

Since 1998 (WW)<br />

5,000<br />

4,500<br />

4,000<br />

3,500<br />

3,000<br />

2,500<br />

2,000<br />

1,500<br />

1,000<br />

500<br />

0<br />

1998<br />

EvaluatePharma<br />

2000<br />

2002<br />

2004<br />

2006<br />

2008<br />

2010E<br />

© Defined Health, 2009<br />

Pain Insight Briefing<br />

2012E<br />

2014E<br />

Avinza<br />

Lyrica<br />

Opana/Opana<br />

ER<br />

Fentora<br />

Jurnista<br />

VIOXX<br />

Celebrex

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