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New MOA Challenges<br />

71<br />

The identification and validation of imaging biomarkers for chronic pain<br />

have lagged behind areas such as oncology, cardiovascular medicine, and<br />

neurology. The Imaging Consortium for Drug Development (ICD) should<br />

help <strong>the</strong> field of pain catch up.<br />

https://meitner.mclean.harvard.edu/<br />

The Imaging Consortium for Drug Development (ICD) is a<br />

collaborative research effort between academia and<br />

pharmaceutical companies who are developing novel drugs to<br />

treat central nervous system (CNS) disorders. The ICD uses<br />

functional MRI (fMRI) to elucidate <strong>the</strong> effects of pain<br />

modulating drugs on neural activity within <strong>the</strong> brain in humans<br />

and in animal models of CNS disease. This landmark effort<br />

builds on more than a decade of fMRI research into <strong>the</strong> study<br />

of pain, and realizes <strong>the</strong> benefits of standardization and costsharing<br />

among consortium members, for pre-competitive<br />

Neuroscience research.<br />

© Defined Health, 2009<br />

Pain Insight Briefing

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