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Addressing <strong>the</strong> Big Problem<br />
67<br />
>50% of Patients Report Suboptimal Relief of Pain<br />
Enter <strong>the</strong> novel mechanisms…<br />
FAAH inhibitors<br />
TRPV1 antagonists/agonists<br />
NGF inhibitors<br />
CCR2 antagonists<br />
KCC2 modulators<br />
O<strong>the</strong>r biological, mediator-based approaches<br />
Defined Health primary research; Adis R&D Insight<br />
© Defined Health, 2009<br />
Pain Insight Briefing